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Human ACCN4 / ASIC4 | |
Rabbit | |
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Zebrafish (tested or 100% immunogen sequence identity) | |
Chicken, Xenopus (at least 90% immunogen sequence identity) | |
Polyclonal | |
Unconjugated. Also available conjugated with Biotin, HRP, FITC. | |
Immunoaffinity purified | |
Unmodified |
ACCN4 / ASIC4 antibody was raised against synthetic peptide located between aa484-533 of human ASIC4 (Q96FT7). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Baboon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Guinea pig, Armadillo (100%); Turkey, Zebra finch, Chicken, Xenopus (92%); Lizard (85%). | ||
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aa484-533 | ||
Human ACCN4 | ||
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody. |
Lyophilized from PBS with 2% sucrose | |
Distilled water | |
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles. | |
For research use only. |
ASIC4 Antibody, ACCN4 Antibody, Acid-sensing ion channel 4 Antibody, BNAC4 Antibody, Brain sodium channel 4 Antibody, Spasic Antibody
ACCN4 / ASIC4 belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.
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