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| Catalog Number | Size | Price |
|---|---|---|
| LS-B156-100 | 100 µl (0.5 mg/ml) | $485 |
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Polyclonal Rabbit anti‑Human ACCN1 / ASIC2 Antibody (aa481‑530, IHC, WB) LS‑B156
Polyclonal Rabbit anti‑Human ACCN1 / ASIC2 Antibody (aa481‑530, IHC, WB) LS‑B156
Note: This antibody replaces LS-C19278
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
ASIC2 antibody LS-B156 is an unconjugated rabbit polyclonal antibody to human ASIC2 (ACCN1) (aa481-530). Validated for IHC and WB. Cited in 5 publications.
Target
Human ACCN1 / ASIC2
Synonyms
ASIC2 | ACCN1 | ASIC2a | Brain sodium channel 1 | Degenerin | ACCN | Acid-sensing ion channel 2 | Mammalian degenerin homolog | MDEG | MDEG1 | MDEG2 | HBNaC1 | BNaC1 | MAMMALIAN DEGENERIN | ASIC2b
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide located between aa481-530 of human ASIC2 (Q16515-2, NP_899233). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Marmoset, Elephant, Bat, Rabbit, Horse (100%); Galago, Mouse, Rat, Bovine, Opossum, Turkey, Chicken (92%); Zebra finch (85%).
Epitope
aa481-530
Specificity
Human ACCN1
Applications
- IHC
- IHC - Paraffin (5 µg/ml)
- Western blot
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B156 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B156 was determined to be 5 ug/ml.
Presentation
PBS, 0.09% sodium azide, 2% sucrose
Storage
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ACCN1 / ASIC2
LSBio Ratings
ACCN1 / ASIC2 Antibody (aa481-530) for IHC, WB/Western LS-B156 has an LSBio Rating of
Publications (4.4)
Learn more about The LSBio Ratings Algorithm
Publications (5)
Acid-sensing ion channels in healthy and degenerated human intervertebral disc. Cuesta A, Del Valle ME, Garc[Character ed]a-Su[Character e1]rez O, Vi[Character f1]a E, Cabo R, V[Character e1]zquez G, Cobo JL, Murcia A, Alvarez-Vega M, Garc[Character ed]a-Cosamal[Character f3]n J, Vega JA. Connective tissue research. 2014 Jun;55:197-204.
Acid-sensing ion channels (ASICs) in the taste buds of adult zebrafish. Vi[Character f1]a E, Parisi V, Cabo R, Laur[Character e0] R, L[Character f3]pez-Velasco S, L[Character f3]pez-Mu[Character f1]iz A, Garc[Character ed]a-Su[Character e1]rez O, German[Character e0] A, Vega JA. Neuroscience letters. 2013 Mar;536:35-40.
Acid-sensing ion channels (ASICs) 2 and 4.2 are expressed in the retina of the adult zebrafish. Parisi V, S[Character e1]nchez-Ramos C, Cabo R, Guerrera MC, Quir[Character f3]s LM, German[Character e0] A, Vega JA, Garc[Character ed]a-Su[Character e1]rez O. Cell and tissue research. Jan;
Acid-sensing ion channel 2 (ASIC2) is selectively localized in the cilia of the non-sensory olfactory epithelium of adult zebrafish. Vi[Character f1]a E, Parisi V, Abbate F, Cabo R, Guerrera MC, Laur[Character e0] R, Quir[Character f3]s LM, P[Character e9]rez-Varela JC, Cobo T, German[Character e0] A, Vega JA, Garc[Character ed]a-Su[Character e1]rez O. Histochemistry and cell biology. 2015 Jan;143:59-68.
Acid-sensing ion channel 2 (asic 2) and trkb interrelationships within the intervertebral disc. Cuesta A, Viña E, Cabo R, Vázquez G, Cobo R, García-Suárez O, García-Cosamalón J, Vega JA. International journal of clinical and experimental pathology. 2015 8:10305-14. (WB; Human)
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Featured Products
Species:
Mouse, Human
Applications:
IHC, IHC - Paraffin
Species:
Mouse, Human, Rat
Applications:
IHC, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Reactivity:
Pig
Range:
0.156-10 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
