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Anti-ACCN1 / ASIC2 Antibody (aa481-530) IHC-plus™ LS-B156

Note: This antibody replaces LS-C19278

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $450
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ACCN1 / ASIC2 Antibodies

Anti-ACCN1 / ASIC2 Antibody (aa481-530) IHC-plus™ LS-B156
Rabbit Polyclonal to Human ACCN1 / ASIC2
Human, Monkey, Bat, Horse, Rabbit
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-ACCN1 / ASIC2 Antibody (C-Terminus) LS-C110053
Rabbit Polyclonal to Human ACCN1 / ASIC2
Human, Monkey, Mouse, Rat, Bovine, Horse, Rabbit, Chicken, Zebrafish
Western blot
Unconjugated
Western blot Image
Anti-ACCN1 / ASIC2 Antibody (aa15-26) IHC-plus™ LS-B4761
Rabbit Polyclonal (IgG) to Mouse ACCN1 / ASIC2
Mouse, Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed Publications Publications (4)
Rabbit Polyclonal to Human ACCN1 / ASIC2
Human, Monkey, Bat, Horse, Rabbit
IHC - Paraffin, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human ACCN1 / ASIC2
Rabbit
Human, Monkey, Bat, Horse, Rabbit (tested or 100% immunogen sequence identity)
Mouse, Rat, Bovine, Chicken (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot
  • (applications tested for the base form of this product only)

Specificity and Use

ACCN1 / ASIC2 antibody was raised against synthetic peptide located between aa481-530 of human ASIC2 (Q16515-2, NP_899233). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Marmoset, Elephant, Bat, Rabbit, Horse (100%); Galago, Mouse, Rat, Bovine, Opossum, Turkey, Chicken (92%); Zebra finch (85%).
LS-E12477 - Lyophilized - 100 µg - $145.00
aa481-530
Human ACCN1
Immunohistochemistry: LS-B156 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B156 was determined to be 5 ug/ml.

Packaging

Lyophilized from PBS with 2% sucrose
50 µl Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

Publications (4)

1
Acid-sensing ion channels in healthy and degenerated human intervertebral disc. Cuesta A, Del Valle ME, Garc[Character ed]a-Su[Character e1]rez O, Vi[Character f1]a E, Cabo R, V[Character e1]zquez G, Cobo JL, Murcia A, Alvarez-Vega M, Garc[Character ed]a-Cosamal[Character f3]n J, Vega JA. Connective tissue research. 2014 Jun;55:197-204. [Full Text Article] [PubMed:24432912]
2
Acid-sensing ion channels (ASICs) in the taste buds of adult zebrafish. Vi[Character f1]a E, Parisi V, Cabo R, Laur[Character e0] R, L[Character f3]pez-Velasco S, L[Character f3]pez-Mu[Character f1]iz A, Garc[Character ed]a-Su[Character e1]rez O, German[Character e0] A, Vega JA. Neuroscience letters. 2013 Mar;536:35-40. [Full Text Article] [PubMed:23328442]
3
Acid-sensing ion channels (ASICs) 2 and 4.2 are expressed in the retina of the adult zebrafish. Parisi V, S[Character e1]nchez-Ramos C, Cabo R, Guerrera MC, Quir[Character f3]s LM, German[Character e0] A, Vega JA, Garc[Character ed]a-Su[Character e1]rez O. Cell and tissue research. Jan; [Full Text Article] [PubMed:25585988]
4
Acid-sensing ion channel 2 (ASIC2) is selectively localized in the cilia of the non-sensory olfactory epithelium of adult zebrafish. Vi[Character f1]a E, Parisi V, Abbate F, Cabo R, Guerrera MC, Laur[Character e0] R, Quir[Character f3]s LM, P[Character e9]rez-Varela JC, Cobo T, German[Character e0] A, Vega JA, Garc[Character ed]a-Su[Character e1]rez O. Histochemistry and cell biology. 2015 Jan;143:59-68. [Full Text Article] [PubMed:25161120]
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About ACCN1 / ASIC2

Q16515 NM_183377 NP_899233.1

ASIC2 Antibody, ACCN1 Antibody, ASIC2a Antibody, Brain sodium channel 1 Antibody, Degenerin Antibody, ACCN Antibody, Acid-sensing ion channel 2 Antibody, Mammalian degenerin homolog Antibody, MDEG Antibody, MDEG1 Antibody, MDEG2 Antibody, HBNaC1 Antibody, BNaC1 Antibody, MAMMALIAN DEGENERIN Antibody

ACCN1 / ASIC2 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission.

Immunohistochemistry

Immunohistochemistry
Anti-ACCN1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B156 concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
ACCN1 antibody LS-B156 Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
A: Marker, B: HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 1/18/2017

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