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ABI1 / SSH3BP1
abl-interactor 1
May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level. In brain, seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons.
| Gene Name: | abl-interactor 1 |
| Synonyms: | ABI1, Abelson interactor 1, Abl-interactor protein 1 long, ABI-1, Abl-interactor 1, Abl interactor 1, Abl-binding protein 4, ABLBP4, NAP1BP, Nap1 binding protein, SSH3BP1, Nap1-binding protein, E3B1, Eps8-binding protein, Interactor protein AblBP4, SSH3BP |
| Target Sequences: | NM_005470 NP_005461.2 Q8IZP0 |
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ABI1 / SSH3BP1
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ABI1 / SSH3BP1 Mouse anti-Human Monoclonal (1B9) Antibody
Mouse, Hamster, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$451
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (aa325-375) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µl/$295; 100 µl/$514
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
ELISA, WB
Unconjugated
0.1 mg/$379
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (aa325-375) Antibody
Human
IHC, IHC-P
Unconjugated
50 µl/$460
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (aa483-494) Antibody
Rabbit, Mouse, Guinea pig, Sheep, Rat, Pig, Horse, Bat, Human, Monkey
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (aa81-108) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100 µg/$564
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, ICC, IF, IHC-P
Unconjugated, Preservative Free
100 µl/$412
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (aa151-175) Antibody
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Horse, Bat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, ICC, WB
Unconjugated
100 µl/$440; 200 µl/$468
ABI1 / SSH3BP1 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
25 µl/$304
ABI1 / SSH3BP1 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$567
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (pTyr435) Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$341
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (aa81-108) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (aa81-108) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (aa81-108) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (aa81-108) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (aa81-108) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (aa81-108) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal (aa152-201) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ABI1 / SSH3BP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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