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Anti-ABCC5 / MRP5 Antibody (aa2-13) IHC-plus™ LS-B2334

Note: This antibody replaces LS-C55118
Catalog Size Price
LS-B2334-50 50 µg (0.5 mg/ml) Unavailable

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100% Guaranteed Publications (1)
Goat Polyclonal to Human ABCC5 / MRP5
Human, Monkey, Bovine, Dog, Horse, Pig, Rabbit, Chicken
IHC - Paraffin, Western blot, ELISA


Human ABCC5 / MRP5
Human, Monkey, Bovine, Dog, Horse, Pig, Rabbit, Chicken (tested or 100% immunogen sequence identity)
Mouse, Rat (at least 90% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (5 µg/ml)
  • Western blot (1:32000) & (0.5 - 1.5 µg/ml)
  • ELISA (1:32000)

Specificity and Use

ABCC5 / MRP5 antibody was raised against synthetic peptide KDIDIGKEYIIP-C from the N-terminus of human ABCC5 / MRP5 (NP_005679.2; NP_001018881.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Dog, Bovine, Elephant, Panda, Horse, Rabbit, Pig, Turkey, Chicken (100%); Mouse, Rat (92%); Hamster (83%).
LS-E26777 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B2334. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human ABCC5 / MRP5. This antibody is expected to recognize both reported isoforms (NP_005679.2; NP_001018881.1).
Immunohistochemistry: LS-B2334 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2334 was determined to be 5 ug/ml.


Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

Publications (1)

Transporter function and cyclic AMP turnover in normal colonic mucosa from patients with and without colorectal neoplasia. Kleberg K, Jensen GM, Christensen DP, Lundh M, Grunnet LG, Knuhtsen S, Poulsen SS, Hansen MB, Bindslev N. BMC gastroenterology. 2012 12:78. (IHC; Human) [Full Text Article] [PubMed:22734885] [PMC:PMC3457850]

About ABCC5 / MRP5

O15440 NM_005688 NP_005679.2

ABCC5 Antibody, ABC33 Antibody, Abcc5a Antibody, MOATC Antibody, MRP5 Antibody, PABC11 Antibody, SMRP Antibody, EST277145 Antibody, MOAT-C Antibody

ABCC5 / MRP5 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides.


Anti-ABCC5 / MRP5 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2334 concentration 5 ug/ml.

Western blot

Western blot
Antibody (0.5 ug/ml) staining of Human Frontal Cortex lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Requested From: 
Date Requested: 3/18/2018

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