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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ABCC4 / MRP4 Antibody (aa70‑82) LS‑C139750
MRP4 antibody LS-C139750 is an unconjugated goat polyclonal antibody to human MRP4 (ABCC4). Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C139750-100
100 µg
Unavailable

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Product Description

MRP4 antibody LS-C139750 is an unconjugated goat polyclonal antibody to human MRP4 (ABCC4). Validated for Peptide-ELISA and WB.
About ABCC4 / MRP4
ABCC4 / MRP4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. O15439 NM_005845 NP_005836.2

ABCC4 Antibody, EST170205 Antibody, MOAT-B Antibody, Multidrug resistance protein 4 Antibody, MOATB Antibody, MRP4 Antibody


Specifications

Target
Human ABCC4 / MRP4
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.3 - 1 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:64000)
Immunogen
ABCC4 / MRP4 antibody was raised against synthetic peptide RAENDAQKPSLTR-C from the N-terminus (near) of human ABCC4 / MRP4 (NP_005836.2; NP_001098985.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (92%).
Blocking Peptide
LS-E27618 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C139750. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa70-82
Specificity
Human ABCC4 / MRP4. This antibody is expected to recognize both reported isoforms (NP_005836.2; NP_001098985.1).
Usage
Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx 100kD band observed in Human Lung and Human Prostate lysates (calculated MW of 96.8kD according to NP_001098985.1). Recommended concentration: 0.3-1 ug/ml.
Presentation
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

ABCC4 antibody (0.3 ug/ml) staining of Human Prostate lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
ABCC4 antibody (0.3 ug/ml) staining of Human Prostate lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

ABCC4 antibody (0.3 ug/ml) staining of Human Prostate lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
ABCC4 antibody (0.3 ug/ml) staining of Human Prostate lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

ABCC4 antibody (0.3 ug/ml) staining of Human Prostate lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
ABCC4 antibody (0.3 ug/ml) staining of Human Prostate lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

ABCC4 antibody (0.3 ug/ml) staining of Human Prostate lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
ABCC4 antibody (0.3 ug/ml) staining of Human Prostate lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


Requested From: 
Date Requested: 6/18/2018

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