Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal (IgG1) to Human ABCB1 / MDR1 / P Glycoprotein
IHC - Paraffin, IHC - Frozen
Human ABCB1 / MDR1 / P Glycoprotein
Human (tested or 100% immunogen sequence identity)
Tissue culture supernatant
IHC - Paraffin
IHC - Frozen
Specificity and Use
ABCB1 / MDR1 / P Glycoprotein antibody was raised against multi-Drug Resistant Chinese hamster cell line (CHrC5).
Recognizes human Multi-Drug Resistance 1.
Suitable for use in Immunohistochemistry. Immunohistochemistry: Frozen and formalin-fixed, paraffin-embedded tissue sections. Epitope retrieval is required using citrate buffer. See protocol. Positive control: Liver/colon.
PBS, pH 7.4, 1% BSA, 0.1% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance.