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Anti-ABCB1 / MDR1 / P Glycoprotein Antibody (clone UIC2) LS-C58240

Note: This antibody replaces LS-C58236


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $295
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular ABCB1 / MDR1 / P Glycoprotein Antibodies

Anti-ABCB1 / MDR1 / P Glycoprotein Antibody (Cytoplasmic Domain) IHC-plus™ LS-A9403
Rabbit Polyclonal to Human ABCB1 / MDR1 / P Glycoprotein
IHC - Paraffin
Immunohistochemistry Image
Anti-ABCB1 / MDR1 / P Glycoprotein Antibody (aa262-277) IHC-plus™ LS-B1448
Rabbit Polyclonal to Human ABCB1 / MDR1 / P Glycoprotein
Human, Monkey, Mouse, Rat, Dog
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image
Anti-ABCB1 / MDR1 / P Glycoprotein Antibody (clone JSB-1) IHC-plus™ LS-B5570
Mouse Monoclonal [clone JSB-1] (IgG1) to Human ABCB1 / MDR1 / P Glycoprotein
IHC - Paraffin, IHC - Frozen, Western blot, Flow Cytometry
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone UIC2] (IgG2a) to Human ABCB1 / MDR1 / P Glycoprotein
Human, Primate
IHC - Paraffin, IHC - Frozen, Immunofluorescence, Immunoprecipitation, Flow Cytometry


Human ABCB1 / MDR1 / P Glycoprotein
Human, Primate (tested or 100% immunogen sequence identity)
Mouse, Rat
IgG2a Monoclonal [UIC2]
Affinity purified


  • IHC - Paraffin
  • IHC - Frozen
  • Immunofluorescence
  • Immunoprecipitation
  • Flow Cytometry (1:50 - 1:200)

Specificity and Use

ABCB1 / MDR1 / P Glycoprotein antibody was raised against mouse Balb/c 3T3 fibroblasts transfected with human CD243 cDNA.
Recognizes an extracellular conformational epitope of CD243, also known as MDR1 (multi-drug resistance protein 1) and Pgp (P-glycoprotein), a transmembrane protein and member of the ABC transporter (ATP-binding cassette) family, which acts as an active efflux pump for a diverse range of lipophillic compounds. CD243 is expressed at low levels in the cell membrane of peripheral blood leucocytes, and constitutively expressed on the apical plasma membrane of excretory epithelial cells of the kidney, liver, brain and small intestine. Strong inhibitor of CD243-mediated efflux and of the resistance of MDR cells to CD243 transported cytotoxic drugs. Can be used in a shift assay to selectively demonstrate the expression and functional activity of CD243 in a target cell. Does not cross-react with mitochondrial pyruvate carboxylase.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100ul. Immunohistochemistry: This product may benefit from antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose (3-4). Histology Positive Control Tissue: Human kidney.


PBS, pH 7.4, 0.09% sodium azide.
Long term: -20°C; Short term: -20°C
For research use only.

About ABCB1 / MDR1 / P Glycoprotein

P08183 NM_000927 NP_000918.2

ABCB1 Antibody, ABC20 Antibody, Abcb1b Antibody, CLCS Antibody, Colchicin sensitivity Antibody, CD243 Antibody, Doxorubicin resistance Antibody, IBD13 Antibody, gp170 Antibody, MDR1 Antibody, Multidrug resistance protein 1 Antibody, P glycoprotein Antibody, P-glycoprotein 1 Antibody, P-GP Antibody, CD243 antigen Antibody, PGY1 Antibody

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance.

Requested From: United States
Date Requested: 10/23/2016

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