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Anti-ABCB1 / MDR1 / P Glycoprotein Antibody (aa262-277) IHC-plus™ LS-B1448

Note: This antibody replaces LS-C18849


Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular ABCB1 / MDR1 / P Glycoprotein Antibodies

Anti-ABCB1 / MDR1 / P Glycoprotein Antibody (Cytoplasmic Domain) IHC-plus™ LS-A9403
Rabbit Polyclonal to Human ABCB1 / MDR1 / P Glycoprotein
IHC - Paraffin
Immunohistochemistry Image
Anti-ABCB1 / MDR1 / P Glycoprotein Antibody (aa262-277) IHC-plus™ LS-B1448
Rabbit Polyclonal to Human ABCB1 / MDR1 / P Glycoprotein
Human, Monkey, Mouse, Rat, Dog
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image
Anti-ABCB1 / MDR1 / P Glycoprotein Antibody (clone JSB-1) IHC-plus™ LS-B5570
Mouse Monoclonal [clone JSB-1] (IgG1) to Human ABCB1 / MDR1 / P Glycoprotein
IHC - Paraffin, IHC - Frozen, Western blot, Flow Cytometry
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed Publications Publications (1)
Rabbit Polyclonal to Human ABCB1 / MDR1 / P Glycoprotein
Human, Monkey, Mouse, Rat, Dog
IHC - Paraffin, Western blot, ELISA


Human ABCB1 / MDR1 / P Glycoprotein
Human, Monkey, Mouse, Rat, Dog (tested or 100% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (5 µg/ml)
  • Western blot (1:200 - 1:2000)
  • ELISA (1:10000 - 1:50000)

Specificity and Use

ABCB1 / MDR1 / P Glycoprotein antibody was raised against synthetic peptide from human ABCB1 / P Glycoprotein.
Amino acids 262-277 of human ABCB1 protein.
Tested in Western blot with recombinant proteins only. Immunohistochemistry: LS-B1448 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1448 was determined to be 5 ug/ml.


0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

Publications (1)

miR-200c inhibits melanoma progression and drug resistance through down-regulation of BMI-1. Liu S, Tetzlaff MT, Cui R, Xu X. The American journal of pathology. 2012 Nov;181:1823-35. [Full Text Article] [PubMed:22982443] [PMC:PMC3483804]

About ABCB1 / MDR1 / P Glycoprotein

P08183 NM_000927 NP_000918.2

ABCB1 Antibody, ABC20 Antibody, Abcb1b Antibody, CLCS Antibody, Colchicin sensitivity Antibody, CD243 Antibody, Doxorubicin resistance Antibody, IBD13 Antibody, gp170 Antibody, MDR1 Antibody, Multidrug resistance protein 1 Antibody, P glycoprotein Antibody, P-glycoprotein 1 Antibody, P-GP Antibody, CD243 antigen Antibody, PGY1 Antibody

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance.


Anti-MDR1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1448 concentration 5 ug/ml.

Western blot

Western blot
Anti-ABCB1 Antibody - Western Blot. Western blot of affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10000. Personal Communication, Anna Calcagno, CCR-NCI, Bethesda, MD.

Requested From: United States
Date Requested: 10/27/2016

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