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Anti-ABCA1 Antibody (aa215-233, clone 3A1-891.3, FITC) LS-C188427

Note: This antibody replaces LS-C124843

Ordering

Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $255
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ABCA1 Antibodies

Anti-ABCA1 Antibody (aa1800-2260, clone A00121.01) IHC-plus™ LS-B2384
Mouse Monoclonal [clone A00121.01] (IgG1) to Human ABCA1
Human, Mouse, Chicken
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-ABCA1 Antibody (aa1100-1300) IHC-plus™ LS-B3038
Rabbit Polyclonal to Human ABCA1
Human, Mouse, Rat, Hamster
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-ABCA1 Antibody (aa2253-2257) LS-C205245
Rabbit Polyclonal to Human ABCA1
Human, Mouse, Rat
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal [clone 3A1-891.3] (IgG1) to Mouse ABCA1
Mouse
Flow Cytometry
FITC Conjugated

Details

Mouse ABCA1
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [3A1-891.3]
Fluorescein
Protein G purified
Unmodified

Applications

Flow Cytometry (1:1 - 1:10)

Specificity and Use

ABCA1 antibody was raised against synthetic peptide corresponding to aa 215-233.
aa215-233
Recognizes murine adenosine triphosphate (ATP) Binding cassette transporter 1 (ABCA1). The ABC transporters are a large family of conserved proteins that transport a wide variety of molecules across cellular membranes. ABCA1 is a member of the ABC-A sub-family, which acts as a lipid translocator. The molecule was originally identified as a scavenger receptor on macrophages and research shows that ABCA1 also plays a major role in cholesterol metabolism. ABCA1 may play an important role in protecting against cardiovascular disease. Mutations in ABCA1 gene have been associated with Tangiers disease, a genetic disorder of lipid metabolism, and familial high density lipoprotein (HDL) deficiency.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, 0.09% sodium azide, 1% BSA
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. Protect from light.
For research use only.

About ABCA1

O95477 NM_005502 NP_005493.2

ABCA1 Antibody, ABC-1 Antibody, ABC1 Antibody, CERP Antibody, HDLDT1 Antibody, Tangier disease Antibody, ATP-binding cassette 1 Antibody, Td Antibody, Membrane-bound Antibody, TGD Antibody

ABCA1 (ATP-binding Cassette, Sub-family A, Member 1), also known as ABC1 (ABC Transporter 1) or CERP (Cholesterol efflux regulatory protein), is a member of the family of ATP-binding cassette (ABC) transporters. It is a cAMP-dependent, sulfonylurea-sensitive traffic ATPase, which is located at the plasma membrane and plays a key role in the cellular lipid removal pathway.

Flow Cytometry

Flow Cytometry
Flow cytometry of pCPT-cAMP stimulated RAW264.7 cells with Rat anti-Mouse ABCA1:FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/3/2016

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