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Anti-AATF Antibody (aa171-220) LS-C29956

Catalog Size Price
LS-C29956-50 50 µg (1 mg/ml) Unavailable

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44 AATF Antibodies

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Anti-AATF Antibody (clone 3C7) IHC-plus™ LS-B11447
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Anti-AATF Antibody (N-Terminus) LS-C353394
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Anti-AATF Antibody LS-C408889
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100% Guaranteed
Rabbit Polyclonal (IgG) to Human AATF
Human, Dog, Horse, Rabbit
IHC - Paraffin, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human AATF
Rabbit
Human, Dog, Horse, Rabbit (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin
  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

AATF antibody was raised against synthetic peptide located between aa171-220 of human AATF (Q9NY61, NP_036270). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Rabbit (100%); Monkey, Elephant (92%); Marmoset (91%); Galago (85%); Bat, Horse (84%).
LS-E11115 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C29956. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa171-220
Human AATF

Packaging

Lyophilized from PBS with 2% sucrose
50 µl After adding water, will consist of PBS buffer with 2% sucrose
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About AATF

Q9NY61 NM_012138 NP_036270.1

AATF Antibody, CHE1 Antibody, DED Antibody, Rb-binding protein Che-1 Antibody, CHE-1 Antibody, Protein AATF Antibody

May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression.

Immunohistochemistry

Immunohistochemistry
AATF antibody LS-C29956 was used in IHC to stain formalin-fixed, paraffin-embedded human intestine. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Immunohistochemistry
AATF antibody LS-C29956 was used in IHC to stain formalin-fixed, paraffin-embedded human liver. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
Fetal Kidney Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 12/10/2017

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