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Anti-AANAT Antibody (phospho-Ser206) LS-C91311

Catalog Size Price
LS-C91311-50 50 µg (1 mg/ml) Unavailable

Related Products

32 AANAT Antibodies

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Anti-AANAT Antibody LS-C2610
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IHC, Western blot
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Immunohistochemistry Image
Anti-AANAT Antibody (phospho-Thr29) LS-C91310
Rabbit Polyclonal (IgG) to Rat AANAT
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Anti-AANAT Antibody (phospho-Ser206) LS-C91311
Rabbit Polyclonal (IgG) to Rat AANAT
Rat
Western blot
Unconjugated
Anti-AANAT Antibody (aa22-236, Biotin) LS-C421310
Rabbit Polyclonal (IgG) to Mouse AANAT
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ICC, Western blot, ELISA
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Anti-AANAT Antibody (aa22-236, FITC) LS-C421311
Rabbit Polyclonal (IgG) to Mouse AANAT
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ICC, Western blot, ELISA
FITC Conjugated

100% Guaranteed
Rabbit Polyclonal (IgG) to Rat AANAT
Rat
Western blot
Unconjugated

Details

Rat AANAT
Rabbit
Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot (0.5 µg/ml)

Specificity and Use

AANAT antibody was raised against synthetic phosphopeptide: CHTFLRRNS(p)GC corresponding to C-terminal amino acid residues 198-208 of rat AA-NAT. This sequence is completely conserved between rat and mouse AA-NAT protein. Percent identity by BLAST analysis: Rat (100%); Human, Chimpanzee, Gorilla, Gibbon, Monkey, Mouse, Hamster, Elephant (89%).
pSer206
Recognizes rat phospho serotonin N-acetyltransferase. Expected to cross-react with mouse due to sequence homology.
Suitable for use in Western Blot. Western Blot: 0.5 ug/ml. Detects a band at ~23kD in rat pineal gland whole protein extract.

Packaging

PBS, 1 mg/ml BSA, 0.05% sodium azide
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About AANAT

Q16613 NM_001088 NP_001079.1

AANAT Antibody, AA-NAT Antibody, DSPS Antibody, Serotonin N-acetyltransferase Antibody, SNAT Antibody, Serotonin acetylase Antibody

AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation.

Requested From: 
Date Requested: 6/25/2017

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