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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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AAK1 Antibody (aa271‑320) LS‑C119088
AAK1 antibody LS-C119088 is an unconjugated rabbit polyclonal antibody to AAK1 from human, mouse and rat. Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C119088-50
50 µl
Unavailable
LS-C119088-100
100 µl
Unavailable

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Product Description

AAK1 antibody LS-C119088 is an unconjugated rabbit polyclonal antibody to AAK1 from human, mouse and rat. Validated for Peptide-ELISA and WB.
About AAK1
Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. Isoform 1 and isoform 2 display similar levels of kinase activity towards AP2M1. Regulates phosphorylation of other AP-2 subunits as well as AP-2 localization and AP-2-mediated internalization of ligand complexes. Q2M2I8 NM_014911 NP_055726.3

AAK1 Antibody, Adaptor-associated kinase 1 Antibody, AP2 associated kinase 1 Antibody, KIAA1048 Antibody


Specifications

Target
Human AAK1
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:20000)
Immunogen
AAK1 antibody was raised against synthetic peptide from human AAK1 (aa271-320).
Epitope
aa271-320
Specificity
AAK1 Antibody detects endogenous levels of total AAK1 protein.
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Customer Reviews (0)


Images


Western blot

Western blot of extracts from COS7 cells, using AAK1 Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COS7 cells, using AAK1 Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from COS7 cells, using AAK1 Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COS7 cells, using AAK1 Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from COS7 cells, using AAK1 Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COS7 cells, using AAK1 Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from COS7 cells, using AAK1 Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COS7 cells, using AAK1 Antibody. The lane on the right is treated with the synthesized peptide.


Requested From: 
Date Requested: 6/20/2018

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