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Anti-AAK1 Antibody (aa271-320) LS-C119088

Ordering

Wt. Vol. Conc. Price
- 50 µl - Unavailable
- 100 µl - Unavailable

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48 AAK1 Antibodies

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Anti-AAK1 Antibody (aa240-320) LS-C381842
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Rabbit Polyclonal (IgG) to Human AAK1
Human, Mouse, Rat
Western blot, ELISA
Unconjugated

Details

Human AAK1
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (1:500 - 1:1000)
  • ELISA (1:20000)

Specificity and Use

AAK1 antibody was raised against synthetic peptide from human AAK1 (aa271-320).
aa271-320
AAK1 Antibody detects endogenous levels of total AAK1 protein.

Packaging

PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Store at -20°C for up to one year.
For research use only.

About AAK1

Q2M2I8 NM_014911 NP_055726.3

AAK1 Antibody, Adaptor-associated kinase 1 Antibody, AP2 associated kinase 1 Antibody, KIAA1048 Antibody

Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. Isoform 1 and isoform 2 display similar levels of kinase activity towards AP2M1. Regulates phosphorylation of other AP-2 subunits as well as AP-2 localization and AP-2-mediated internalization of ligand complexes.

Western blot

Western blot
Western blot of extracts from COS7 cells, using AAK1 Antibody. The lane on the right is treated with the synthesized peptide.

Requested From: 
Date Requested: 4/26/2017

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