Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Recognizes Estradiol-17-beta. No cross-reactivity is seen with estrone, esrriol, estrone sulphate, 16-ketoestradiol, 2-hydroxyestradiol, progesterone, androstenedione, testosterone, or cortisol when measuring on tritium-labeled steroids in radioimmunoassay. Epitope specific for the hormone, no reactivity to the CMO linker. Reacts specifically with estradiol-17beta with a measured Ka of 3x10E9 in a radioimmunoassay. Can be cleaved with papain and reduced to generate Fab fragments with a Ka of 13.4x10E9.
Suitable for use in ELISA and Radioimmunoassay. ELISA: 1:4000. RIA: Specifically reacts with estradiol-17beta with a measured Ka of 3x10^9.