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ANAPC11 / APC11 Antibody (C-Terminus) LS-C19022

Antibody

ANAPC11 / APC11 Antibody (C-Terminus) LS-C19022

Antibody:
Rabbit Polyclonal to Human ANAPC11 / APC11
Application:
WB, IP, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$425 
LS-C19022-100
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human ANAPC11 / APC11
Application:
WB, IP, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
APC11 antibody LS-C19022 is an unconjugated rabbit polyclonal antibody to human APC11 (ANAPC11). Validated for ELISA, IP and WB. Cited in 2 publications.

Target
Human ANAPC11 / APC11
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Delipidated and defibrinated
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
  • Immunoprecipitation
  • ELISA (1:2000 - 1:10000)
Immunogen
ANAPC11 / APC11 antibody was raised against synthetic peptide from human ANAPC11 / APC11.
Epitope
C-Terminus
Specificity
Amino acids 76-84 of Human APC11 (C-terminal) coupled to KLH.
Usage
This antibody reacts with human APC11 by western blot and immunoprecipitation. The antibody immunoprecipitates in vitro translated protein and protein from overexpressing cell lysates (using HeLa and NIH-3T3, and others). Coimmunoprecipitation of related proteins (APC2) does occur. A 9.8 kD band corresponding to human APC11 is detected. Most cell lines or tissues expressing APC11 can be used as a positive control. Researchers should determine optimal titers for other applications.
Presentation
0.01% Sodium Azide
Storage
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid freeze-thaw cycles. Centrifuge product if not completely clear after standing at room temperature.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ANAPC11 / APC11
Q9NYG5 NM_016476 NP_057560.8

Publications (2)

Association with cullin partners protects ROC proteins from proteasome-dependent degradation. Ohta T, Michel JJ, Xiong Y. Oncogene. 1999 18:6758-66.

Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins. Furukawa M, Ohta T, Xiong Y. The Journal of biological chemistry. 2002 277:15758-65.

Reviews (0)

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Requested From: United States
Date Requested: 7/19/2019
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