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ANAPC1 / APC1
anaphase promoting complex subunit 1
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
| Gene Name: | anaphase promoting complex subunit 1 |
| Synonyms: | ANAPC1, APC1, Cyclosome subunit 1, MCPR, Mitotic checkpoint regulator, TSG24 |
| Target Sequences: | NM_022662 NP_073153.1 Q9H1A4 |
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Antibodies
(25)
Proteins
(1)
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Primary
(25)
Recombinant
(1)
Target
ANAPC1 / APC1
(26)
Reactivity
Human
(25)
Mouse
(19)
Rat
(8)
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(1)
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(1)
Application
IHC
(17)
IHC-P
(8)
WB
(10)
Flo
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ELISA
(16)
ICC
(2)
IF
(10)
IP
(3)
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(5)
Host
rabbit
(23)
mouse
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Product Group
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(3)
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IgG
(21)
IgG1
(2)
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monoclonal mc
(2)
polyclonal pc
(23)
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7G9B3
(1)
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Unconjugated
(25)
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pSer355
(3)
290-370 aa
(2)
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(2)
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(2)
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(1)
aa1311-1360
(1)
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(1)
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(1)
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pSer377
(1)
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(26)
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Wheat Germ Extract
(1)
ANAPC1 / APC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (pSer377) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$515
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (630-710 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (aa500-550) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
ANAPC1 / APC1 Mouse anti-Human Monoclonal (7G9B3) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
100 µl/$459
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (aa654-703) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (pSer688) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ANAPC1 / APC1 Mouse anti-Human Monoclonal (7G9C7) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (630-710 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (pSer688) Antibody
Mouse, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
ANAPC1 / APC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
100 µl/$299
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (Glu684) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P
Unconjugated
50 µl/$321; 100 µl/$403
ANAPC1 / APC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (290-370 aa) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (290-370 aa) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ANAPC1 / APC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF
Unconjugated
100 µg/$357
ANAPC1 / APC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$567
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (aa321-370) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (pSer355) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (pSer355) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
100 µg/$357
ANAPC1 / APC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
100 µg/$357
![ANAPC1 / APC1 Antibody - Anti-APC1 pS355 Antibody - Western Blot. Western blot of Affinity Purified anti-APC1 pS355 antibody shows detection of a band ~215 kD corresponding to phosphorylated human APC1 (arrowhead). Lane 1 shows lysate from asynchronous cells. Lane 2 shows lysate from cells treated with thymidine to synchronize cells at the G1/S boundary. Lane 3 shows lysate from cells treated with nocodazole to synchronize cells at the M phase. Phosphorylated APC1 is mostly present only in cell preparations arrested at cell division. Each lane contains approximately 30 ug of HeLa S3 whole cell lysates separated by 12.5% SDS-PAGE followed by transfer to nitrocellulose. After blocking with 5% non-fat dry milk in TTBS, the membrane was probed with the primary antibody diluted to 1:500 for 1 h at room temperature followed by washes and reaction with a 1:5000 dilution of HRP Gt-a-Rabbit IgG [H&L] MX (LS-C60865) for 45 min at room temperature. ECL reagent was used for detection. Other detection systems will yield similar results. Data contributed by Bing Li, UT Southwestern.](https://lsbio-7d62.kxcdn.com/image2/anapc1-apc1-antibody-phospho-ser355-ls-c18983/62894_5054667.jpg)
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (pSer355) Antibody
Mouse, Dog, Bovine, Rat, Human
ELISA, IP, WB
Unconjugated
100 µg/$567
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (aa1311-1360) Antibody
Mouse, Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ANAPC1 / APC1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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