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Catalog Number Size Price
LS-C387997-100 100 µg $480 
AMD / AMD1 Antibody - IHC-P: AMD1 antibody testing of human breast cancer tissue
AMD / AMD1 Antibody - Western blot testing of AMD1 antibody and Lane 1: rat kidney; 2: HeLa; Predicted size: 38KD; Observed size: 38KD
AMD / AMD1 Antibody - IHC-P: AMD1 antibody testing of human breast cancer tissue
AMD / AMD1 Antibody - Western blot testing of AMD1 antibody and Lane 1: rat kidney; 2: HeLa; Predicted size: 38KD; Observed size: 38KD
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Polyclonal Rabbit anti‑Human AMD / AMD1 Antibody (aa315‑330, IHC, WB) LS‑C387997

Polyclonal Rabbit anti‑Human AMD / AMD1 Antibody (aa315‑330, IHC, WB) LS‑C387997

Antibody:
AMD / AMD1 Rabbit anti-Human Polyclonal (aa315-330) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep
Format:
Unconjugated, Unmodified
Price
Catalog Number
$480
LS-C387997-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
AMD / AMD1 Rabbit anti-Human Polyclonal (aa315-330) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep
Format:
Unconjugated, Unmodified

Specifications

Description
AMD1 antibody LS-C387997 is an unconjugated rabbit polyclonal antibody to AMD1 (AMD) (aa315-330) from human. It is reactive with human, mouse, rat and other species. Validated for IHC and WB.
Target
Human AMD / AMD1
Synonyms
AMD1 | ADOMETDC | AMD | SAMDC
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from the C-Terminus of human AMD1 (FNDYNFVFTSFAKKQQ, aa315-330 of UniProt P17707). Percent identity by BLAST analysis: Human, Mouse, Rat, Ferret, Sheep, Cat, Bovine, Bat, Hamster, Rabbit, Horse, Pig, Guinea pig, Lizard, Dog (100%); Elephant, Opossum, Platypus, Catfish (94%); Xenopus, Trout, Salmon, Zebrafish (88%); Turkey, Stickleback (81%).
Epitope
aa315-330
Specificity
Human AMD / AMD1
Applications
  • IHC
  • IHC - Paraffin (0.5 - 1 µg/ml)
  • Western blot (0.5 - 1 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
S-adenosylmethionine decarboxylase (AdoMet-DC), also known as S-adenosylmethionine decarboxylase proenzyme (SAMDC), is a key enzyme in polyamine biosynthesis. It is localized to chromosome region 6q21-q22. SAMDC has an unusual distribution in polysomes from cells of T lymphocyte origin. It associates predominantly with monosomes and small polysomes with none located in the preribosomal or ribonucleoprotein pool. SAMDC is a critical regulatory enzyme of the polyamine synthetic pathway, and a well-studied drug target. Since SAMDC is a key regulatory enzyme in the synthesis of spermidine and spermine, the marked increase in SAMDC activity in the neonate and the sustained high enzyme levels throughout adulthood, imply a role for these polyamines in both development and mature brain function.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About AMD / AMD1
P17707 NM_001634 NP_001625.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/27/2021