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Catalog Number Size Price
LS-C387963-100 100 µg $506 
Alpha Catenin Antibody - IHC-P staining of rat intestine tissue
Alpha Catenin Antibody - IHC-P: alpha Catenin antibody testing of mouse intestine tissue
Alpha Catenin Antibody - IHC-P: alpha Catenin antibody testing of human breast tissue
Alpha Catenin Antibody - Western blot testing of alpha Catenin antibody and recombinant human protein (0.5ng)
Alpha Catenin Antibody - Western blot testing of alpha Catenin antibody and Lane 1: rat liver; 2: (r) lung; 3: (r) heart; 4: mouse NIH3T3; 5: (r) PC12; 6: human HEPG2; 7: (h) HeLa; 8: (h) MCF-7; 9: (m) HEPA. Expected/observed size ~102KD
Alpha Catenin Antibody - IHC-P staining of rat intestine tissue
Alpha Catenin Antibody - IHC-P: alpha Catenin antibody testing of mouse intestine tissue
Alpha Catenin Antibody - IHC-P: alpha Catenin antibody testing of human breast tissue
Alpha Catenin Antibody - Western blot testing of alpha Catenin antibody and recombinant human protein (0.5ng)
Alpha Catenin Antibody - Western blot testing of alpha Catenin antibody and Lane 1: rat liver; 2: (r) lung; 3: (r) heart; 4: mouse NIH3T3; 5: (r) PC12; 6: human HEPG2; 7: (h) HeLa; 8: (h) MCF-7; 9: (m) HEPA. Expected/observed size ~102KD
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Polyclonal Rabbit anti‑Human Alpha Catenin Antibody (aa143‑292, IHC, WB) LS‑C387963

Polyclonal Rabbit anti‑Human Alpha Catenin Antibody (aa143‑292, IHC, WB) LS‑C387963

Antibody:
Alpha Catenin Rabbit anti-Human Polyclonal (aa143-292) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$506
LS-C387963-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Alpha Catenin Rabbit anti-Human Polyclonal (aa143-292) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
Alpha Catenin antibody LS-C387963 is an unconjugated rabbit polyclonal antibody to Alpha Catenin (aa143-292) from human. It is reactive with human, mouse and rat. Validated for IHC and WB.
Target
Human Alpha Catenin
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Human partial recombinant protein (aa143-292).
Epitope
aa143-292
Specificity
Human Alpha Catenin
Applications
  • IHC
  • IHC - Paraffin (0.5 - 1 µg/ml)
  • IHC - Frozen (0.5 - 1 µg/ml)
  • Western blot (0.5 - 1 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Alpha Catenin is a protein that in humans is encoded by the CTNNA1 gene. When surface epithelium CTNNA1 was ablated, hair follicle development was blocked and epidermal morphogenesis was dramatically affected, with defects in adherens junction formation, intercellular adhesion, and epithelial polarity. In vitro, CTNNA1 null keratinocytes were poorly contact inhibited and grew rapidly. These differences were not dependent upon intercellular adhesion and were in marked contrast to keratinocytes conditionally null for another essential intercellular adhesion protein, desmoplakin Knockout keratinocytes exhibited sustained activation of the Ras-MAPK cascade due to aberrations in growth factor responses. It is concluded that features of precancerous lesions often attributed to defects in cell cycle regulatory genes can be generated by compromising the function of CTNNA1.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/26/2021