ALOX15 / 15-Lipoxygenase

arachidonate 15-lipoxygenase

Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes. In parallel, may regulate actin polymerization which is crucial for several biological processes, including macrophage function. May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway. Finally, it is also involved in the cellular response to IL13/interleukin-13. In addition to its role in the immune and inflammatory responses, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4. May also play a role in endoplasmic reticulum stress response and the regulation of bone mass.

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Antibodies (48)

ELISA Kits (11)

Proteins (5)

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Custom (3)

Over-Expression Lysate (2)

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Recombinant (3)

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Sandwich CLIA (1)

Target

ALOX15 / 15-Lipoxygenase (64)

Reactivity

Human (53)

Mouse (12)

Rat (8)

Chimpanzee (3)

Dog (2)

Gibbon (3)

Guinea pig (1)

Monkey (7)

Orangutan (3)

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IHC (20)

IHC-P (8)

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ICC (1)

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Peptide-ELISA (2)

Host

rabbit (25)

mouse (22)

goat (1)

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IHCPlus (3)

Isotype

IgG (18)

IgG2a (2)

IgG2a,k (6)

IgG2b (6)

Clonality

monoclonal mc (22)

polyclonal pc (26)

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3D8 (1)

7H6 (2)

OTI2G3 (2)

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OTI8C5 (2)

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96-Well Strip Plate (9)

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Epitope

aa170-312 (16)

aa539-588 (4)

aa2-337 (1)

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aa610-643 (1)

Publications

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Yes (1)

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His (1)

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293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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Purified (1)

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IHC-plus™ ALOX15 / 15-Lipoxygenase Antibody (clone 7H6) LS-B12236

(5.0) Rating

(1) Publication(s)

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (7H6) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ ALOX15 / 15-Lipoxygenase Antibody (clone 3D8) LS-B4278

(4.0) Rating

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (3D8) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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ALOX15 / 15-Lipoxygenase Antibody (clone OTI2G3) LS-C173699

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (OTI2G3) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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ALOX15 / 15-Lipoxygenase Antibody (clone OTI2G3, Carrier-free) LS-C786815

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (Carrier-free) (OTI2G3) Antibody

Reactivity:

Human

Applications:

Flo, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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ALOX15 / 15-Lipoxygenase Antibody (aa610-643) LS-C99452

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal (aa610-643) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$393

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ALOX15 / 15-Lipoxygenase Antibody (aa2-337) LS-C343940

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal (aa2-337) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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ALOX15 / 15-Lipoxygenase Antibody (aa170-312) LS-C292930

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal (aa170-312) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141

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ALOX15 / 15-Lipoxygenase Antibody (aa170-312, Biotin) LS-C300672

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal (aa170-312) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$308; 200 µl/$350; 500 µl/$489; 1 ml/$558; 2 ml/$749; 5 ml/$1,217

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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Human ALOX15 / 15-Lipoxygenase (Sandwich ELISA) ELISA Kit - LS-F9552

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$764

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ALOX15 / 15-Lipoxygenase Antibody (aa539-588) LS-C111783

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal (aa539-588) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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IHC-plus™ ALOX15 / 15-Lipoxygenase Antibody (aa482-494) LS-B6689

(4.0) Rating

Antibody:

ALOX15 / 15-Lipoxygenase Goat anti-Human Polyclonal (aa482-494) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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Human ALOX15 / 15-Lipoxygenase (Sandwich ELISA) ELISA Kit - LS-F23767

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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ALOX15 / 15-Lipoxygenase Antibody (clone 7H6, Carrier-free) LS-C786937

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (Carrier-free) (7H6) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

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ALOX15 / 15-Lipoxygenase Antibody (clone OTI3G8) LS-C173722

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (OTI3G8) Antibody

Reactivity:

Dog, Rat, Human, Monkey

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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ALOX15 / 15-Lipoxygenase Antibody (clone OTI3G8, Carrier-free) LS-C786848

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (Carrier-free) (OTI3G8) Antibody

Reactivity:

Dog, Rat, Human, Monkey

Applications:

IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

ALOX15 / 15-Lipoxygenase Antibody (aa170-312, Biotin) LS-C299109

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (aa170-312) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$314; 200 µl/$359; 500 µl/$506; 1 ml/$580; 2 ml/$797; 5 ml/$1,295

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ALOX15 / 15-Lipoxygenase Antibody (aa170-312, FITC) LS-C304832

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (aa170-312) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$342; 200 µl/$399; 500 µl/$587; 1 ml/$725; 2 ml/$962; 5 ml/$1,647

• Biotin
• FITC

• Biotin
• FITC

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ALOX15 / 15-Lipoxygenase Antibody LS-C659218

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

Human ALOX15 / 15-Lipoxygenase (Sandwich ELISA) ELISA Kit - LS-F36593

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

ALOX15 / 15-Lipoxygenase Antibody (HRP) LS-C543422

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

100 µl/$904

Select

ALOX15 / 15-Lipoxygenase Antibody (Biotin) LS-C523294

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

ALOX15 / 15-Lipoxygenase Antibody (FITC) LS-C533334

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

ALOX15 / 15-Lipoxygenase Antibody (PE) LS-C651532

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

100 µl/$904

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ALOX15 / 15-Lipoxygenase Antibody (APC) LS-C515037

Antibody:

ALOX15 / 15-Lipoxygenase Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

100 µl/$904

• HRP
• Biotin
• FITC
• PE
• APC

• HRP
• Biotin
• FITC
• More...
  • PE
  • APC

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ALOX15 / 15-Lipoxygenase Antibody LS-C349291

Antibody:

ALOX15 / 15-Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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