ALOX12 / 12 Lipoxygenase

arachidonate 12-lipoxygenase

Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like (12S)-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process, promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation.

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Antibodies (36)

ELISA Kits (8)

Proteins (6)

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Custom (2)

Over-Expression Lysate (2)

Primary (36)

Recombinant (4)

Sandwich (5)

Sandwich CLIA (1)

Target

ALOX12 / 12 Lipoxygenase (50)

Reactivity

Human (43)

Mouse (4)

Rat (3)

Chimpanzee (3)

Gibbon (3)

Monkey (3)

Application

IHC (7)

IHC-P (3)

WB (29)

Flo (1)

ELISA (5)

IF (4)

Host

rabbit (28)

mouse (8)

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IHCPlus (1)

Isotype

IgG (19)

IgG1 (4)

IgG2a (2)

IgG2a,k (1)

Clonality

monoclonal mc (7)

polyclonal pc (29)

Clone

2D10 (1)

OTI1B2 (2)

OTI1C3 (2)

OTI5H2 (2)

Format

12 x 8-Well Microstrips (1)

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APC Conjugated (2)

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PE Conjugated (2)

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Epitope

aa352-656 (8)

aa578-627 (4)

aa609-628 (1)

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Cell Lysates (2)

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Serum (4)

Tissue Homogenates (4)

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GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

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Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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IHC-plus™ ALOX12 / 12 Lipoxygenase Antibody (aa618-650) LS-B10714

(4.0) Rating

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (aa618-650) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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ALOX12 / 12 Lipoxygenase Antibody (aa578-627) LS-C81851

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (aa578-627) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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ALOX12 / 12 Lipoxygenase Antibody LS-C833341

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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ALOX12 / 12 Lipoxygenase Antibody LS-C306215

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$705

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ALOX12 / 12 Lipoxygenase Antibody LS-C749685

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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ALOX12 / 12 Lipoxygenase Antibody LS-C680154

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

ALOX12 / 12 Lipoxygenase Antibody (HRP) LS-C680156

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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ALOX12 / 12 Lipoxygenase Antibody (Biotin) LS-C680155

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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ALOX12 / 12 Lipoxygenase Antibody (FITC) LS-C680157

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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Human ALOX12 / 12 Lipoxygenase Protein (Recombinant His-T7) (aa352-656) - LS-G14519

Source:

E. coli

Tag:

His-T7

Molecular Weight:

38.4 kDa

Price:

10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257

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Human ALOX12 / 12 Lipoxygenase Protein (Recombinant GST) (Full Length) - LS-G27427

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

102.1 kDa

Price:

10 µg/$479; 25 µg/$670

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ALOX12 / 12 Lipoxygenase Antibody (clone OTI1C3) LS-C340376

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Monoclonal (OTI1C3) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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ALOX12 / 12 Lipoxygenase Antibody (clone OTI1C3, Carrier-free) LS-C799600

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Monoclonal (Carrier-free) (OTI1C3) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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ALOX12 / 12 Lipoxygenase Antibody (clone 2D10) LS-C196646

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Monoclonal (2D10) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

ALOX12 / 12 Lipoxygenase Antibody (clone OTI1B2) LS-C794119

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Monoclonal (OTI1B2) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

100 µl/$434

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ALOX12 / 12 Lipoxygenase Antibody (clone OTI1B2, Carrier-free) LS-C791373

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Monoclonal (Carrier-free) (OTI1B2) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

ALOX12 / 12 Lipoxygenase Antibody (clone OTI5H2) LS-C340386

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Monoclonal (OTI5H2) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

ALOX12 / 12 Lipoxygenase Antibody (clone OTI5H2, Carrier-free) LS-C791386

Antibody:

ALOX12 / 12 Lipoxygenase Mouse anti-Human Monoclonal (Carrier-free) (OTI5H2) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

ALOX12 / 12 Lipoxygenase Antibody LS-C309424

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

Select

ALOX12 / 12 Lipoxygenase Antibody (Biotin) LS-C520707

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

Select

ALOX12 / 12 Lipoxygenase Antibody (PE) LS-C648950

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$937

• Unconjugated
• Biotin
• PE

• Unconjugated
• Biotin
• PE

Select

ALOX12 / 12 Lipoxygenase Antibody (aa352-656) LS-C314862

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (aa352-656) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

Select

ALOX12 / 12 Lipoxygenase Antibody (aa609-628) LS-C392516

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal (aa609-628) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$575

Select

ALOX12 / 12 Lipoxygenase Antibody LS-C662147

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

ALOX12 / 12 Lipoxygenase Antibody LS-C782971

Antibody:

ALOX12 / 12 Lipoxygenase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$575

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