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Catalog Number Size Price
LS-C357856-25 25 µg (0.5 mg/ml) $323 
LS-C357856-100 100 µg (0.5 mg/ml) $452 
AIMP1 / EMAP II Antibody - EMAP II antibody western blot of human samples

Polyclonal Rabbit anti‑Human AIMP1 / EMAP II Antibody (C‑Terminus, WB) LS‑C357856

Polyclonal Rabbit anti‑Human AIMP1 / EMAP II Antibody (C‑Terminus, WB) LS‑C357856

Antibody:
AIMP1 / EMAP II Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$323
LS-C357856-25
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
AIMP1 / EMAP II Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
EMAP II antibody LS-C357856 is an unconjugated rabbit polyclonal antibody to EMAP II (AIMP1) (C-Terminus) from human. It is reactive with human, mouse and rat. Validated for WB.
Target
Human AIMP1 / EMAP II
Synonyms
AIMP1 | EMAP II | EMAPII | EMAP-2 | HLD3 | p43 | EMAP2 | SCYE1
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Immunogen
A recombinant protein fragment from the C-Terminus of human EMAP II.
Epitope
C-Terminus
Specificity
Human AIMP1 / EMAP II
Applications
  • Western blot (2 - 5 µg/ml)
Usage
EMAP II (Endothelial monocyte-activating polypeptide 2) is a pro-inflammatory cytokine and participant in apoptotic cell death. It is synthesized as a precursor (pro-EMAP II), lacking a secretion signal peptide. In apoptotic cells, the ~34 kDa pro-form of EMAP II is cleaved by Caspase-7 (and Caspase-3 to a lesser extent) at aspartate 144 to its mature, ~20 kDa form. The mature form of EMAP II has been found to have many different functions. In vivo, it recruits leukocytes to the site of apoptotic cell death. In vitro it has been shown to activate endothelial cells (and the release of von Willebrand factor, E-selectin and P-selectin), neutrophils, and induces macrophage expression of TNFa and TF (tissue factor). EMAP II is also a possible biomarker for brain injury, having been found to be differentially expressed in two types: traumatic injury shows an increase and ischemic injury shows a decrease in EMAP II expression (Dave, et al, 2014).
Presentation
1X PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About AIMP1 / EMAP II
Q12904 NM_004757 NP_004748.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/30/2021