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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-C44907-0.1 0.1 mg $375 
Antibody

Monoclonal Hamster anti‑Human ADGRE3 / EMR3 Antibody (clone 3D7, FITC) LS‑C44907

Monoclonal Hamster anti‑Human ADGRE3 / EMR3 Antibody (clone 3D7, FITC) LS‑C44907

Note: This antibody replaces LS-C57640
Antibody:
Hamster Monoclonal to Human ADGRE3 / EMR3
Application:
Flo
Reactivity:
Human
Format:
FITC, Unmodified
Other formats:
Price
Catalog Number
$375 
LS-C44907-0.1
0.1 mg
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Hamster Monoclonal to Human ADGRE3 / EMR3
Application:
Flo
Reactivity:
Human
Format:
FITC, Unmodified
Other formats:

Specifications

Description
EMR3 antibody LS-C44907 is an FITC-conjugated hamster monoclonal antibody to human EMR3 (ADGRE3). Validated for Flow.
Target
Human ADGRE3 / EMR3
Synonyms
ADGRE3 | EGF-like module receptor 3 | EMR3
Host
Hamster
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Monoclonal
Clone
3D7
Conjugations
FITC. Also available Unconjugated.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Flow Cytometry (1:1 - 1:10)
  • Applications tested for the base form of this product only
Immunogen
ARHO-EMR3-CD97 (EGF1) transfectants
Specificity
Recognizes human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 (EMR3), which is a 56kD member of the EGF-7 transmembrane (TM7) family of adhesion receptors. EMR3 is expressed at the cell surface as a heterodimer. The molecule is predominantly expressed on granulocytes, and at lower levels on mature myeloid cells, monocytes and dendritic cells. EMR3 is absent on lymphocytes, hematopoietic stem cells and myeloid progenitors. Studies suggest that the EMR3 molecule is up-regulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells. The exact functions of EMR3 and its ligands have not yet been determined.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Presentation
PBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Do not use frost-free freezers. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ADGRE3 / EMR3
Q9BY15 NM_032571 NP_115960.2

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Requested From: United States
Date Requested: 7/11/2020