Human ADGRE3 / EMR3
ADGRE3 | EGF-like module receptor 3 | EMR3
(tested or 100% immunogen sequence identity)
Also available Unconjugated
Protein G purified
- Flow Cytometry (1:1 - 1:10)
- Applications tested for the base form of this product only
ARHO-EMR3-CD97 (EGF1) transfectants
Recognizes human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 (EMR3), which is a 56kD member of the EGF-7 transmembrane (TM7) family of adhesion receptors. EMR3 is expressed at the cell surface as a heterodimer. The molecule is predominantly expressed on granulocytes, and at lower levels on mature myeloid cells, monocytes and dendritic cells. EMR3 is absent on lymphocytes, hematopoietic stem cells and myeloid progenitors. Studies suggest that the EMR3 molecule is up-regulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells. The exact functions of EMR3 and its ligands have not yet been determined.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
PBS, 0.09% Sodium Azide
Store at 4°C or at -20°C. Store undiluted. Do not use frost-free freezers. Protect from light. Microcentrifugation recommended if solution contains precipitate.
For research use only. Intended for use by laboratory professionals.
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