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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ADGRE2 / EMR2 Antibody (N‑Terminus) IHC‑plus™ LS‑A1663
EMR2 antibody LS-A1663 is an unconjugated rabbit polyclonal antibody to human EMR2 (ADGRE2). Validated for ELISA, ICC and IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-A1663-50
50 µg (1 mg/ml)
$425
In Stock for Immediate Shipment

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Product Description

ADGRE2 / EMR2 Antibody (N-Terminus) for ELISA, ICC, IHC IHC-plus™ LS-A1663

Specifications

Target
Human ADGRE2 / EMR2
Synonyms
ADGRE2, CD312 antigen, EMR2, EGF-like module receptor 2, CD312
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (7.5 - 15 µg/ml)
  • ICC
  • ELISA
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ADGRE2 / EMR2 antibody was raised against synthetic 20 amino acid peptide from N-terminal extracellular domain of human EMR2. Percent identity with other species by BLAST analysis: Human (100%); Gorilla (90%).
Blocking Peptide
LS-E28369 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A1663. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
Human EMR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MYO18B (45%), FLJ13231 (40%).
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About ADGRE2 / EMR2
ADGRE2 / EMR2 is a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. Q9UHX3 NM_013447 NP_038475.2


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Images

Immunocytochemistry

Immunocytochemistry

Immunocytochemistry

Immunocytochemistry

Immunohistochemistry

Anti-EMR2 antibody LS-A1663 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-EMR2 antibody LS-A1663 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunocytochemistry

Immunocytochemistry

Immunocytochemistry

Immunocytochemistry

Immunohistochemistry

Anti-EMR2 antibody LS-A1663 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-EMR2 antibody LS-A1663 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunocytochemistry

Immunocytochemistry

Immunocytochemistry

Immunocytochemistry

Immunohistochemistry

Anti-EMR2 antibody LS-A1663 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-EMR2 antibody LS-A1663 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunocytochemistry

Immunocytochemistry

Immunocytochemistry

Immunocytochemistry

Immunohistochemistry

Anti-EMR2 antibody LS-A1663 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-EMR2 antibody LS-A1663 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: United States
Date Requested: 10/15/2018

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