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ADCYAP1R1 / PAC1 Receptor
adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
The PACAP receptor type 1, a member of the vasoactive intestinal polypeptide subfamily, binds the hormone pituitary adenylate cyclase activating polypeptide (PACAP) with high affinity. PACAP is involved in stimulating the secretion of insulin, catecholamines, ACTH, and growth hormone. Additionally, PACAP appears to function as a neuromodulator/neurotransmitter in the central and peripheral nervous systems. Two start codons are reported in literature, one (nt 74-76) results in a 525-amino acid protein with a signal peptide of 77 amino acids encoded by nt 74-304 and the second (nt 245-247) initiates a 468-amino acid protein with a signal peptide of 20-amino acids encoded by nt 245-304. The efficiency of these two start codons is not known.
| Gene Name: | adenylate cyclase activating polypeptide 1 (pituitary) receptor type I |
| Family/Subfamily: | GPCR , Vasoactive intestinal polypeptide |
| Synonyms: | ADCYAP1R1, PAC1, Pac1 receptor, Pac1 receptors, PAC1-R, PACAP receptor 1, Pacap specific receptor, PACAP-R-1, PACAP/VIP receptors, PACAP1 receptor, PACAP Receptor, Pacap receptor type 1, Pacap type 1 receptor, PACAP type I receptor, PACAPR, PAC1R, PACAP-R1, PACAPRI, Pvr1, Pacap receptor type i |
| Target Sequences: | NM_001118 NP_001109.2 P41586 |
Publications (1)
1
The Potential of Asiatic Acid in the Reversion of Cyclophosphamide-Induced Hemorrhagic Cystitis in Rats. Andrzej Wróbel, Lukasz Zapala, Tomasz Kluz, Artur Rogowski, Marcin Misiek, Kajetan Juszczak, Jacek Sienko, Daniela Gold, Klaudia Stangel-Wójcikiewicz, Ewa Poleszak, Piotr Radziszewski. International journal of molecular sciences. 2021 May;22: [Full Text Article]
[PubMed:34072606]
[PMC:PMC8198845]
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Fast Shipping
ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
Fast Shipping
ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Bovine, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
Fast Shipping
ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Xenopus, Chicken, Bat, Dog, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
Fast Shipping
ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
ADCYAP1R1 / PAC1 Receptor Mouse anti-Human Monoclonal (aa21-120) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
ADCYAP1R1 / PAC1 Receptor Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
ADCYAP1R1 / PAC1 Receptor Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
ADCYAP1R1 / PAC1 Receptor Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
ADCYAP1R1 / PAC1 Receptor Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
ADCYAP1R1 / PAC1 Receptor Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (Extracellular) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$468
ADCYAP1R1 / PAC1 Receptor Mouse anti-Human Monoclonal (2B12) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
HEK 293 Cells
Human IgG Fc, C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human ADCYAP1R1/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 373 amino acids and has a predicted molecular mass of 42 kDa. The reduced monomer migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions due to glycosylation.
50 µg/$441
ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
100 µl/$412
ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (aa343-392) Antibody
Human
WB
Unconjugated
100 µl/$424
ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (aa343-392) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
HRP Conjugated
100 µl/$469
ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (aa343-392) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (aa343-392) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
FITC Conjugated
100 µl/$469
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