ADAMTS4

ADAM metallopeptidase with thrombospondin type 1 motif, 4

ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.

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Products

Antibodies (79)

ELISA Kits (18)

Proteins (7)

Type

Custom (2)

Over-Expression Lysate (2)

Primary (79)

Recombinant (5)

Sandwich (15)

Sandwich CLIA (1)

Target

ADAMTS4 (104)

Reactivity

Human (80)

Mouse (26)

Rat (16)

Bat (6)

Bovine (8)

Chicken (1)

Chimpanzee (6)

Dog (7)

Gibbon (6)

Guinea pig (2)

Hamster (1)

Horse (10)

Monkey (11)

Orangutan (3)

Pig (7)

Porcine (1)

Rabbit (8)

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Application

IHC (18)

IHC-P (15)

WB (60)

ELISA (24)

IF (1)

IP (12)

Neut (1)

Peptide-ELISA (1)

Host

rabbit (53)

mouse (24)

goat (2)

Product Group

IHCPlus (5)

PathPlus Cancer (1)

Isotype

IgG (37)

IgG1 (8)

IgG1,k (7)

IgG2a (2)

Clonality

monoclonal mc (24)

polyclonal pc (55)

Clone

1995CT113.89.78 (1)

OTI2D5 (2)

OTI2G8 (2)

OTI6F1 (2)

OTI6F8 (2)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (3)

96-Well Strip Plate (14)

APC (2)

APC Conjugated (5)

Azide-free (1)

Biotin Conjugated (9)

Carrier-free (4)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (8)

HRP Conjugated (8)

Magnetic beads Conjugated (1)

PE Conjugated (5)

Preservative Free (1)

Sepharose Conjugated (1)

Unconjugated (38)

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Epitope

aa437-575 (16)

aa296-577 (8)

aa705-736 (7)

C-Terminus (5)

aa101-150 (4)

aa56-105 (4)

Internal (3)

aa213-685 (2)

Disintegrin-like Domain (1)

aa693-802 (1)

aa820-837 (1)

aa876-893 (1)

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Publications

No (104)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (1)

Plasma (11)

Serum (11)

Tissue Homogenates (5)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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PathPlus™ ADAMTS4 Antibody (Disintegrin-like Domain) LS-A7773

Cancer

Fast Shipping

(5.0) Rating

Antibody:

ADAMTS4 Rabbit anti-Human Polyclonal (Disintegrin-like Domain) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Hamster, Horse, Bat, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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Rat ADAMTS4 (Sandwich ELISA) ELISA Kit - LS-F9386

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$893

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ADAMTS4 Antibody (aa213-685) LS-C124923

Antibody:

ADAMTS4 Mouse anti-Human Monoclonal (aa213-685) Antibody

Reactivity:

Human

Applications:

ELISA, IP, Neut, WB

Format:

Unconjugated

Price:

500 µg/$1,079

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IHC-plus™ ADAMTS4 Antibody (C-Terminus) LS-A1551

Fast Shipping

(4.0) Rating

Antibody:

ADAMTS4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Dog, Horse, Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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Human ADAMTS4 (Sandwich ELISA) ELISA Kit - LS-F13089

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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IHC-plus™ ADAMTS4 Antibody (Internal) LS-A1548

Fast Shipping

(4.0) Rating

Antibody:

ADAMTS4 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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ADAMTS4 Antibody (aa213-685, Biotin) LS-C124922

Antibody:

ADAMTS4 Goat anti-Human Polyclonal (aa213-685) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

50 µg/$973

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IHC-plus™ ADAMTS4 Antibody (Internal) LS-A1550

Fast Shipping

(4.0) Rating

Antibody:

ADAMTS4 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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Rabbit ADAMTS4 (Sandwich ELISA) ELISA Kit - LS-F25568

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$893

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Human ADAMTS4 (Sandwich ELISA) ELISA Kit - LS-F10525

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

625 - 40000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$795

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Human ADAMTS4 (Sandwich ELISA) ELISA Kit - LS-F7250

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$834

Select

ADAMTS4 Antibody (aa101-150) LS-B11888

Antibody:

ADAMTS4 Rabbit anti-Human Polyclonal (aa101-150) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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ADAMTS4 Antibody LS-C750097

Antibody:

ADAMTS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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ADAMTS4 Antibody (C-Terminus) LS-C172045

Antibody:

ADAMTS4 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$341

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ADAMTS4 Antibody (aa437-575) LS-C292358

Antibody:

ADAMTS4 Mouse anti-Human Monoclonal (aa437-575) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$314; 200 µl/$359; 500 µl/$507; 1 ml/$581; 2 ml/$798; 5 ml/$1,296

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ADAMTS4 Antibody (aa437-575, Biotin) LS-C298077

Antibody:

ADAMTS4 Rabbit anti-Human Polyclonal (aa437-575) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348

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ADAMTS4 Antibody LS-C659768

Antibody:

ADAMTS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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ADAMTS4 Antibody LS-C369225

Antibody:

ADAMTS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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IHC-plus™ ADAMTS4 Antibody (Internal) LS-A1549

Fast Shipping

(4.0) Rating

Antibody:

ADAMTS4 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Dog, Horse, Bat, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

ADAMTS4 Antibody (aa296-577, clone OTI6F8, Carrier-free) LS-C799545

Antibody:

ADAMTS4 Mouse anti-Human Monoclonal (aa296-577) (Carrier-free) (OTI6F8) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

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ADAMTS4 Antibody LS-C662170

Antibody:

ADAMTS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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ADAMTS4 Antibody LS-C809624

Antibody:

ADAMTS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

ADAMTS4 Antibody LS-C782772

Antibody:

ADAMTS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

Select

ADAMTS4 Antibody LS-C63662

Antibody:

ADAMTS4 Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$929

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ADAMTS4 Antibody LS-C332140

Antibody:

ADAMTS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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