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ACKR4 / CCRL1 / CCR11

atypical chemokine receptor 4

Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25. Chemokine-binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization. Plays an important role in controlling the migration of immune and cancer cells that express chemokine receptors CCR7 and CCR9, by reducing the availability of CCL19, CCL21, and CCL25 through internalization. Negatively regulates CXCR3-induced chemotaxis. Regulates T-cell development in the thymus.

Gene Name: atypical chemokine receptor 4
Family/Subfamily: GPCR , Chemokine
Synonyms: ACKR4, C-C CKR-11, CC-CKR-11, CC chemokine receptor-like 1, CCR11, CCX CKR, C-C chemokine receptor type 11, CKR-11, CCRL1, VSHK1, CCR-11, CCX-CKR, PPR1
Target Sequences: NM_016557 NP_057641.1 Q9NPB9

☰ Filters
Antibodies (23)
ELISA Kits (13)
Proteins (1)
Competitive EIA (1)
Primary (23)
Recombinant (1)
Sandwich (10)
Sandwich CLIA (2)
ACKR4 / CCRL1 / CCR11 (37)
Human (24)
Mouse (15)
Rat (8)
Bat (1)
Bovine (3)
Chicken (1)
Chimpanzee (6)
Dog (1)
Gibbon (6)
Guinea pig (1)
Horse (1)
Monkey (4)
Pig (4)
Porcine (1)
Rabbit (5)
IHC (4)
IHC-Fr (1)
IHC-P (4)
WB (20)
ELISA (5)
ICC (1)
IF (9)
Peptide-ELISA (4)
rabbit (21)
mouse (1)
goat (1)
Product Group
GPCR Database Antibodies (2)
IHCPlus (1)
PathPlus Neuro (1)
IgG (8)
IgG2b,k (1)
monoclonal mc (1)
polyclonal pc (22)
1G4 (1)
12 x 8-Well Microstrips (2)
96-Well Microplate (2)
96-Well Strip Plate (9)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (17)
C-Terminus (9)
Cytoplasmic Domain (2)
20-100 aa, N-terminal (1)
260-340 aa, C-terminal (1)
N-Terminus (1)
aa291-340 (1)
aa4-31 (1)
aa47-96 (1)
aa5-54 (1)
No (37)
Plasma (8)
Serum (8)
Tissue Homogenates (2)
GST (1)
Human (1)
Wheat Germ Extract (1)
Purified (1)
ACKR4 / CCRL1 / CCR11 Antibody - Anti-ACKR4 / CCRL1 / CCR11 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Rabbit, Mouse, Dog, Rat, Pig, Horse, Bat, Human
IHC, IHC-P
Unconjugated
50 µg/$440
ACKR4 / CCRL1 / CCR11 Antibody - Anti-ACKR4 / CCRL1 / CCR11 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
ACKR4 / CCRL1 / CCR11 Antibody - Immunofluorescent analysis of CCR11 staining in HEK293T cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 ??C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ICC, IF, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
ACKR4 / CCRL1 / CCR11 Antibody - Western blot of CCRL1 antibody
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (260-340 aa, C-terminal) Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ACKR4 / CCRL1 / CCR11 Antibody - Western blot of CCRL1 antibody
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (20-100 aa, N-terminal) Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ACKR4 / CCRL1 / CCR11 Antibody - Immunofluorescence analysis of COS7 cells, using CCRL1 Antibody. The picture on the right is blocked with the synthesized peptide.
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (aa5-54) Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ACKR4 / CCRL1 / CCR11 Antibody - IHC of CCRL1 / CCR11 antibody. Formalin-fixed, paraffin-embedded mouse lung.
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ACKR4 / CCRL1 / CCR11 Goat anti-Human Polyclonal (aa4-31) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$556
ACKR4 / CCRL1 / CCR11 Antibody - Immunofluorescence analysis of MCF7 cells, using CCRL1 Antibody. The picture on the right is blocked with the synthesized peptide.
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (aa291-340) Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ACKR4 / CCRL1 / CCR11 Antibody - Western blot analysis of the lysates from HepG2 cells using CCRL1 antibody.
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (aa47-96) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ACKR4 / CCRL1 / CCR11 Antibody - CCRL1 antibody Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
ACKR4 / CCRL1 / CCR11 Antibody - CCRL1 antibody Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rat, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
ACKR4 / CCRL1 / CCR11 Antibody - CCRL1 antibody Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rat, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
ACKR4 / CCRL1 / CCR11 Antibody - CCRL1 antibody Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rat, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
ACKR4 / CCRL1 / CCR11 Antibody - CCRL1 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
ACKR4 / CCRL1 / CCR11 Antibody - CCRL1 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Bovine, Pig, Gibbon, Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
ACKR4 / CCRL1 / CCR11 Antibody - CCRL1 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Bovine, Pig, Gibbon, Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
ACKR4 / CCRL1 / CCR11 Antibody - CCRL1 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Bovine, Pig, Gibbon, Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
ACKR4 / CCRL1 / CCR11 Antibody - Western blot analysis of CCR11 expression in HeLa (A); SW480 (B); HepG2 (C) whole cell lysates.
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$299
ACKR4 / CCRL1 / CCR11 Antibody - Staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ACKR4 / CCRL1 / CCR11 Antibody - Clone 1G4 human brain cortex, paraffin section
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ACKR4 / CCRL1 / CCR11 Mouse anti-Human Monoclonal (1G4) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
100 µg/$595
ACKR4 / CCRL1 / CCR11 Antibody - Peptide - + Immunofluorescence analysis of COS-7 cells, using CCRL1 antibody.
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
ACKR4 / CCRL1 / CCR11 Antibody - Peptide - + Immunofluorescence analysis of MCF-7 cells, using CCRL1 antibody.
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
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ACKR4 / CCRL1 / CCR11 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
100 µl/$386
ACKR4 / CCRL1 / CCR11 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
ACKR4 / CCRL1 / CCR11 ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Viewing 1-25 of 37 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).