ACIN1 / Acinus

apoptotic chromatin condensation inducer 1

Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets; ACIN1 confers RNA-binding to the complex. The ASAP complex can inhibit RNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function. Induces apoptotic chromatin condensation after activation by CASP3. Regulates cyclin A1, but not cyclin A2, expression in leukemia cells.

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Products

Antibodies (22)

Proteins (5)

Type

Over-Expression Lysate (4)

Primary (22)

Recombinant (1)

Target

ACIN1 / Acinus (27)

Reactivity

Human (21)

Mouse (9)

Rat (3)

Dog (3)

Gibbon (3)

Monkey (4)

Application

IHC (6)

IHC-P (4)

WB (18)

Flo (1)

DB (2)

ELISA (9)

ICC (6)

IF (5)

IP (1)

Peptide-ELISA (1)

Host

rabbit (19)

mouse (3)

Product Group

IHCPlus (1)

PathPlus Cancer (2)

Isotype

IgG (10)

IgG1 (3)

Clonality

monoclonal mc (3)

polyclonal pc (19)

Clone

2005C3a (2)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (19)

Epitope

aa201-250 (4)

C-Terminus (2)

aa1291-C-term (2)

N-Terminus (1)

Publications

No (27)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (4)

Species

Human (3)

Source

293T Cells (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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PathPlus™ ACIN1 / Acinus Antibody LS-B3190

Cancer

(5.0) Rating

Antibody:

ACIN1 / Acinus Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$440

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PathPlus™ ACIN1 / Acinus Antibody LS-B3189

Cancer

(5.0) Rating

Antibody:

ACIN1 / Acinus Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$440

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ACIN1 / Acinus Antibody (aa201-250) LS-C146438

Antibody:

ACIN1 / Acinus Rabbit anti-Mouse Polyclonal (aa201-250) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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ACIN1 / Acinus Antibody (aa201-250, HRP) LS-C464783

Antibody:

ACIN1 / Acinus Rabbit anti-Mouse Polyclonal (aa201-250) (HRP) Antibody

Reactivity:

Mouse, Dog, Human, Monkey, Gibbon

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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ACIN1 / Acinus Antibody (aa201-250, Biotin) LS-C464781

Antibody:

ACIN1 / Acinus Rabbit anti-Mouse Polyclonal (aa201-250) (Biotin) Antibody

Reactivity:

Mouse, Dog, Human, Monkey, Gibbon

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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ACIN1 / Acinus Antibody (aa201-250, FITC) LS-C464784

Antibody:

ACIN1 / Acinus Rabbit anti-Mouse Polyclonal (aa201-250) (FITC) Antibody

Reactivity:

Mouse, Dog, Human, Monkey, Gibbon

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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ACIN1 / Acinus Antibody LS-C328

Antibody:

ACIN1 / Acinus Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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ACIN1 / Acinus Antibody (clone 2005C3a) LS-C342840

Antibody:

ACIN1 / Acinus Mouse anti-Human Monoclonal (2005C3a) Antibody

Reactivity:

Human

Applications:

DB, ICC, IF, WB

Format:

Unconjugated

Price:

100 µg/$486

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ACIN1 / Acinus Antibody LS-C63517

Antibody:

ACIN1 / Acinus Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, WB

Format:

Unconjugated

Price:

100 µg/$786

Select

IHC-plus™ ACIN1 / Acinus Antibody (C-Terminus) LS-B224

(4.0) Rating

Antibody:

ACIN1 / Acinus Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

ACIN1 / Acinus Antibody LS-C373

Antibody:

ACIN1 / Acinus Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

0.1 mg/$460

Select

ACIN1 / Acinus Antibody (clone 2005C3a) LS-C184346

Antibody:

ACIN1 / Acinus Mouse anti-Human Monoclonal (2005C3a) Antibody

Reactivity:

Human

Applications:

DB, ICC, WB

Format:

Unconjugated

Price:

100 µg/$965

Select

ACIN1 / Acinus Antibody (aa1291-C-term) LS-C287834

Antibody:

ACIN1 / Acinus Rabbit anti-Human Polyclonal (aa1291-C-term) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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ACIN1 / Acinus Antibody LS-C406093

Antibody:

ACIN1 / Acinus Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

ACIN1 / Acinus Antibody (N-Terminus) LS-C46981

Antibody:

ACIN1 / Acinus Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$379

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ACIN1 / Acinus Antibody LS-C778767

Antibody:

ACIN1 / Acinus Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

ACIN1 / Acinus Antibody LS-C778964

Antibody:

ACIN1 / Acinus Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

ACIN1 / Acinus Antibody LS-C807582

Antibody:

ACIN1 / Acinus Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

ACIN1 / Acinus Antibody (aa1291-C-term) LS-C286464

Antibody:

ACIN1 / Acinus Rabbit anti-Human Polyclonal (aa1291-C-term) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

Select

ACIN1 / Acinus Antibody (C-Terminus) LS-C11737

Antibody:

ACIN1 / Acinus Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$558

Select

ACIN1 / Acinus Antibody LS-C760916

Antibody:

ACIN1 / Acinus Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$263; 100 µl/$315; 200 µl/$379

Select

ACIN1 / Acinus Antibody LS-C815808

Antibody:

ACIN1 / Acinus Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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Human ACIN1 / Acinus Protein (Recombinant GST, N-terminus) (aa1-110) - LS-G61895

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

2 µg/$439

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Human ACIN1 / Acinus Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90094

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.8 kDa

Price:

20 µg/$150

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Human ACIN1 / Acinus Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90095

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.4 kDa

Price:

20 µg/$150

Viewing 1-25 of 27 product results

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