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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ACE / CD143 Antibody (N‑Terminus, FITC) LS‑C3720
CD143 antibody LS-C3720 is an FITC-conjugated mouse monoclonal antibody to CD143 (ACE) from human, rat, cat and other species. Validated for Flow.
Antibody
Catalog
Size
Price
LS-C3720-100
100 µg
$650

Popular ACE / CD143 Products

Anti-ACE antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2558 concentration 10 ug/ml.
Species: Human, Monkey, Mouse, Rat, Bovine, Cat, Dog, Guinea pig, Rabbit
Applications: IHC, IHC - Paraffin, Western blot
Anti-ACE / CD143 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10663 dilution 1:100.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
Western blot of ACE1 antibody
Species: Human, Mouse, Rat
Applications: IHC, Western blot, ELISA
Antibody
Species: Human, Mouse, Bovine
Applications: IHC, Flow Cytometry, ELISA
Antibody
Species: Human, Monkey, Rat, Cat, Hamster
Applications: IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot, Immunoprecipitation, ELISA

Product Description

CD143 antibody LS-C3720 is an FITC-conjugated mouse monoclonal antibody to CD143 (ACE) from human, rat, cat and other species. Validated for Flow.

Specifications

Target
Human ACE / CD143
Synonyms
ACE, ACE1, Angiotensin-converting enzyme, CD143, CD143 antigen, Carboxycathepsin, DIPEPTIDYL CARBOXYPEPTIDASE, DCP, Dipeptidyl carboxypeptidase I, ICH, Kininase II, MVCD3, Peptidyl-dipeptidase A, Peptidase P, DCP1, Dipeptidyl carboxypeptidase 1, Testicular ECA
Host
Mouse
Reactivity
Human, Monkey, Rat, Cat, Hamster (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Fluorescein. Also available Unconjugated or conjugated with AP, APC, Biotin, FITC, HRP, PE, Biotin, Biotin, FITC, FITC, PE, PE, Biotin, Biotin, PE.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Flow Cytometry
  • (applications tested for the base form of this product only)
Immunogen
ACE / CD143 antibody was raised against human lung CD143.
Epitope
N-Terminus
Specificity
Recognizes human CD143, also know as angiotensin-converting enzyme (ACE). CD143 exists in two forms, a 170kD somatic form and a 90kD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa. This antibody recognizes active ACE binding to an N-terminal domain epitope, different to that recognized by clone i2H5. Species cross-reactivity: Human, monkey, rat, hamster, feline.
Usage
Flow Cytometry: Neat. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
Purified IgG.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About ACE / CD143
ACE / CD143 is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. P12821 NM_000789 NP_000780.1


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Requested From: United States
Date Requested: 10/17/2018

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