CD143 antibody LS-C3715 is an unconjugated mouse monoclonal antibody to CD143 (ACE) from human, rat, cat and other species. Validated for ELISA, Flow, IHC and IP.
Human, Monkey, Rat, Cat, Hamster
(tested or 100% immunogen sequence identity)
Tissue culture supernatant
- IHC - Frozen
- Flow Cytometry
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ACE / CD143 antibody was raised against human lung CD143 (Angiotensin converting enzyme).
Recognizes human somatic CD143, also know as angiotensin-converting enzyme (ACE). CD143 exists in two forms, a 170kD somatic form and a 90kD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa. This antibody recognizes active ACE binding to an N-terminal domain epitope, different to that recognized by clone i2H5. Species cross-reactivity: Human, monkey, rat, hamster, feline.
Flow Cytometry: Neat -1:10. Immunohistochemistry (Frozen). ELISA. Immunoprecipitation. Positive control: Kidney.
Tissue Culture Supernatant. Supplied as a liquid, 0.1% sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.