Target
Human ACAN / Aggrecan
Synonyms
ACAN | AGCAN | Aggrecan core protein | Acg1 | Aggrecan | CSPG1 | CSPGCP | CSPCP | AGC1 | Aggrecan 1 | Large aggregating proteoglycan | MSK16 | SEDK | MCSPG
Reactivity
Human, Monkey, Rat, Bat, Bovine, Dog, Pig, Rabbit
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
Unconjugated.
Also available conjugated with
AP,
APC,
Biotin,
FITC,
HRP,
PE.
Purification
Protein A purified
Immunogen
FFGVGGEEDC-KLH peptide. Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Rat, Panda, Bat, Bovine, Dog, Rabbit, Pig (100%); Mouse (89%).
Specificity
Recognizes human Aggrecan, a neo-epitope on polypeptides with N-terminal FFGVG Sequences. By immunoblotting, specifically detects G2 fragments derived from an aggrecan G1-G2 substrate digested with stromelysin, collagenase, gelatinase and matrilysin, but does not detect G2 fragments obtained from elastase, trypsin, or cathepsin B digests. Undigested G1-G2 was not detected. Competition experiments confirmed that peptides containing internal FFGVG sequences were not detected by the antibody.
Usage
Suitable for use in Western Blot and ELISA.
Presentation
PBS, pH 7.6, 0.1% Sodium Azide
Storage
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee