Human ABCB2 / TAP1
TAP1 | ABC17 | ABCB2 | APT1 | D6S114E | ABC transporter, MHC 1 | Ham1 | Peptide transporter TAP1 | PSF1 | TAP1N | MTP1 | Peptide transporter PSF1 | PSF-1 | Peptide supply factor 1 | RING4 | Y3
(tested or 100% immunogen sequence identity)
TAP1 peptide corresponding to the C-Terminus of human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
Detects an epitope within the C-terminal region of human TAP1, also known as transporter associated with antigen processing 1. TAP1 is an 81kD membrane-associated protein which is a member of the ATP-binding cassette (ABC) transporter superfamily and together with the homologous subunit TAP2 forms the functional TAP complex. TAP1 is involved in the transport of antigenic peptides from the cytosol into the endoplasmic reticulum, where they associate with major histocompatibility complex (MHC) class I molecules. These complexes are presented at the cell surface to T-lymphocytes, which identify and remove infected or malignantly transformed cells. AHP1248 does not cross react with TAP2.