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Anti-LRP2 / Megalin Antibody (aa4641-4655) IHC-plus™ LS-B105

Note: This antibody replaces LS-C3335


Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395

LSBio (Direct) LSBio (Direct)

Other LRP2 / Megalin Products

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Rabbit Polyclonal to Human LRP2 / Megalin
IHC - Paraffin, ELISA


Human LRP2 / Megalin
Human (tested or 100% immunogen sequence identity)
Protein G purified


IHC - Paraffin (2.5 µg/ml), ELISA (1:1000)

Specificity and Use

LRP2 / Megalin antibody was raised against synthetic peptide from human LRP2 / Megalin.
Immunohistochemistry: LS-B105 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B105 was determined to be 2.5 ug/ml.


PBS, 0.1% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

Publications (1)

Apelin retards the progression of diabetic nephropathy. Day RT, Cavaglieri RC, Feliers D. American journal of physiology. Renal physiology. 2013 Mar;304:F788-800. [Full Text Article] [PubMed:23303408] [PMC:PMC3602700]

About LRP2 / Megalin

P98164 NM_004525 NP_004516.2

LRP2 Antibody, DBS Antibody, Glycoprotein 330 Antibody, gp330 Antibody, Megalin Antibody, LRP-2 Antibody, Calcium sensor protein Antibody

LRP2 / Megalin, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail.


Anti-Megalin antibody IHC of human kidney cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B105 concentration 5 ug/ml.

Requested From: United States
Date Requested: 11/28/2015

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