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Anti-GPR49 / LGR5 Antibody (Internal, clone EPR3065Y) LS-C105455

Note: This antibody replaces LS-C92468

Ordering

Wt. Vol. Conc. Price
- 100 µl 0.041 mg/ml $495

LSBio (Direct) LSBio (Direct)
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GPR49 / LGR5 Antibody LS-C105455 Images

[click image for a larger image and more details]
Western blot
Western blot analysis on fetal skeletal muscle lysate using anti-GPR49 antibody (LS-C105455),...

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Rabbit Monoclonal [clone EPR3065Y] (IgG) to Human GPR49 / LGR5
Human, Mouse, Rat
Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated

Details

Human GPR49 / LGR5
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Monoclonal [EPR3065Y]
Tissue culture supernatant

Applications

Western blot (1:500 - 1:1000), Immunoprecipitation (1:20), Flow Cytometry (1:1000)

Specificity and Use

GPR49 / LGR5 antibody was raised against a synthetic peptide corresponding to residues in human GPR49 was used as an immunogen.
Internal
Recognizes LGR5 (GPR49)

Packaging

Tris-Glycine-NaCl or PBS, pH 7.2-7.4, 40-50% Glycerol, 0.01% sodium azide, 0.05% BSA
Store at -20°C. Aliquot to avoid freeze/thaw cycles. Store undiluted.
For research use only.

About GPR49 / LGR5

O75473 NM_003667 NP_003658.1

LGR5 Antibody, FEX Antibody, G-protein coupled receptor 49 Antibody, G protein-coupled receptor 49 Antibody, GPR67 Antibody, GRP49 Antibody, GPR49 Antibody, HG38 Antibody, G-protein coupled receptor 67 Antibody

Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.

Western blot

Western blot
Western blot analysis on fetal skeletal muscle lysate using anti-GPR49 antibody (LS-C105455), dilution 1:1000.
 
Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Requested From: United States
Date Requested: 7/28/2015

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