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Unfortunately, the antibody LS-C191336 is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



TP / Thymidine Phosphorylase Antibodies

thymidine phosphorylase

This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene Name: thymidine phosphorylase
Synonyms: TYMP Antibody, ECGF1 Antibody, HPD-ECGF Antibody, MEDPS1 Antibody, MNGIE Antibody, MTDPS1 Antibody, PD-ECGF Antibody, Thymidine phosphorylase Antibody, PDECGF Antibody, ECGF Antibody, Gliostatin Antibody, TdRPase Antibody, TP Antibody
Target Sequences: NM_001953 NP_001944.1 P19971
 TP / Thymidine Phosphorylase Feature Table
Featured Image

Featured TP / Thymidine Phosphorylase Antibody

LS-B9812 is a mouse monoclonal antibody that LifeSpan has tested extensively in immunohistochemistry (IHC) and is an excellent antibody for use in formalin-fixed paraffin embedded tissues. Multiple tissues were immunolabeled and the results were interpreted by a LifeSpan pathologist. This image shows an example of staining in formalin-fixed paraffin embedded tissue. Learn more about our IHC Validation procedure. All LSBio antibodies are 100% guaranteed.

Publications (1)

1
Expression of thymidine phosphorylase in lymph nodes involved with mycosis fungoides and szary syndrome. Nie X, Bhat R, Al-Saleem ED, Vonderheid EC, Hou JS. Advances in hematology. 2011 2011:875135. [PubMed:22162690] [PMC:PMC3226296]

TP / Thymidine Phosphorylase Antibodies (34)

Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
TP / Thymidine Phosphorylase Mouse IgG1 Monoclonal P-GF.44C Unconjugated Human, Mouse, Rat IHC-P, WB No Primary
Anti-TP / Thymidine Phosphorylase Antibody (clone P-GF.44C) IHC-plus™ LS-B9812
IHC Image
Mouse Monoclonal [clone P-GF.44C] (IgG1) to Human TP / Thymidine Phosphorylase
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
TP / Thymidine Phosphorylase Mouse IgG1 Monoclonal 7A6 Unconjugated Human IHC-P, WB No Primary
Anti-TP / Thymidine Phosphorylase Antibody (clone 7A6) LS-C175522
IHC Image
IHC Image
Mouse Monoclonal [clone 7A6] (IgG1) to Human TP / Thymidine Phosphorylase
Human
IHC - Paraffin, Western blot
Unconjugated
TP / Thymidine Phosphorylase Mouse IgG1 Monoclonal 1H7 Unconjugated Human IHC-P, WB No Primary
Anti-TP / Thymidine Phosphorylase Antibody (clone 1H7) LS-C175520
IHC Image
IHC Image
Mouse Monoclonal [clone 1H7] (IgG1) to Human TP / Thymidine Phosphorylase
Human
IHC - Paraffin, Western blot
Unconjugated
TP / Thymidine Phosphorylase Mouse IgG1 Monoclonal 5B5 Unconjugated Human IHC-P, WB No Primary
Anti-TP / Thymidine Phosphorylase Antibody (clone 5B5) LS-C175523
IHC Image
IHC Image
Mouse Monoclonal [clone 5B5] (IgG1) to Human TP / Thymidine Phosphorylase
Human
IHC - Paraffin, Western blot
Unconjugated
TP / Thymidine Phosphorylase Mouse IgG1 Monoclonal 7B4 Unconjugated Human IHC-P, WB No Primary
Anti-TP / Thymidine Phosphorylase Antibody (clone 7B4) LS-C175340
IHC Image
IHC Image
Mouse Monoclonal [clone 7B4] (IgG1) to Human TP / Thymidine Phosphorylase
Human
IHC - Paraffin, Western blot
Unconjugated
TP / Thymidine Phosphorylase Mouse IgG1 Monoclonal 5B11 Unconjugated Human IHC-P, WB No Primary
Anti-TP / Thymidine Phosphorylase Antibody (clone 5B11) LS-C175539
IHC Image
IHC Image
Mouse Monoclonal [clone 5B11] (IgG1) to Human TP / Thymidine Phosphorylase
Human
IHC - Paraffin, Western blot
Unconjugated
TP / Thymidine Phosphorylase Mouse IgG1 Monoclonal 1H10 Unconjugated Human IHC-P, WB No Primary
Anti-TP / Thymidine Phosphorylase Antibody (clone 1H10) LS-C175519
IHC Image
IHC Image
Mouse Monoclonal [clone 1H10] (IgG1) to Human TP / Thymidine Phosphorylase
Human
IHC - Paraffin, Western blot
Unconjugated
TP / Thymidine Phosphorylase Mouse IgG1 Monoclonal 1G10 Unconjugated Human IHC-P, WB No Primary
Anti-TP / Thymidine Phosphorylase Antibody (clone 1G10) LS-C175514
IHC Image
IHC Image
Mouse Monoclonal [clone 1G10] (IgG1) to Human TP / Thymidine Phosphorylase
Human
IHC - Paraffin, Western blot
Unconjugated
TP / Thymidine Phosphorylase Rabbit Polyclonal Unconjugated Human IHC-P, WB Internal No Primary
Anti-TP / Thymidine Phosphorylase Antibody (Internal) LS-C100879
IHC Image
WB Image
Rabbit Polyclonal to Human TP / Thymidine Phosphorylase
Human
IHC - Paraffin, Western blot
Unconjugated
TP / Thymidine Phosphorylase Mouse IgG1 Monoclonal 4F4 Unconjugated Human IHC-P, WB No Primary
Anti-TP / Thymidine Phosphorylase Antibody (clone 4F4) LS-C175544
IHC Image
WB Image
Mouse Monoclonal [clone 4F4] (IgG1) to Human TP / Thymidine Phosphorylase
Human
IHC - Paraffin, Western blot
Unconjugated
TP / Thymidine Phosphorylase Mouse IgG1 Monoclonal P-GF.44C Unconjugated Human, Mouse, Rat IHC-P No Primary
Anti-TP / Thymidine Phosphorylase Antibody (clone P-GF.44C) LS-C88222
IHC Image
Mouse Monoclonal [clone P-GF.44C] (IgG1) to Human TP / Thymidine Phosphorylase
Human, Mouse, Rat
IHC - Paraffin
Unconjugated
TP / Thymidine Phosphorylase Mouse IgG1 Monoclonal P-GF.44C Unconjugated Human WB No Primary
Anti-TP / Thymidine Phosphorylase Antibody (clone P-GF.44C) LS-C95495
IHC Image
Mouse Monoclonal [clone P-GF.44C] (IgG1) to Human TP / Thymidine Phosphorylase
Human
Western blot
Unconjugated
TP / Thymidine Phosphorylase Mouse IgG1 Monoclonal Unconjugated Human, Mouse, Rat IHC-P, IHC-Fr, WB No Primary
Anti-TP / Thymidine Phosphorylase Antibody LS-C92761
Mouse Monoclonal (IgG1) to Human TP / Thymidine Phosphorylase
Human, Mouse, Rat
IHC - Paraffin, IHC - Frozen, Western blot
Unconjugated
TP / Thymidine Phosphorylase Goat IgG Polyclonal Unconjugated Human IHC, WB, ELISA No Primary
Anti-TP / Thymidine Phosphorylase Antibody LS-C150025
Goat Polyclonal (IgG) to Human TP / Thymidine Phosphorylase
Human
IHC, Western blot, ELISA
Unconjugated
TP / Thymidine Phosphorylase Mouse IgG1 Monoclonal P-GF.44C Unconjugated, Azide-free Human, Mouse, Rat IHC-P No Primary
Anti-TP / Thymidine Phosphorylase Antibody (clone P-GF.44C, Azide-free) LS-C88223
Mouse Monoclonal [clone P-GF.44C] (IgG1) to Human TP / Thymidine Phosphorylase
Human, Mouse, Rat
IHC - Paraffin
Unconjugated, Azide-free
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal HRP Conjugated, Azide-free Human IHC, WB, ELISA No Primary
Anti-TP / Thymidine Phosphorylase Antibody (Azide-free, HRP) LS-C277041
Rabbit Polyclonal (IgG) to Human TP / Thymidine Phosphorylase
Human
IHC, Western blot, ELISA
HRP Conjugated, Azide-free
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal FITC Conjugated Human IHC, WB, ELISA No Primary
Anti-TP / Thymidine Phosphorylase Antibody (FITC) LS-C277040
Rabbit Polyclonal (IgG) to Human TP / Thymidine Phosphorylase
Human
IHC, Western blot, ELISA
FITC Conjugated
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal Unconjugated Human IHC, WB, ELISA Internal No
Anti-TP / Thymidine Phosphorylase Antibody (Internal) LS-C330422
Rabbit Polyclonal (IgG) to Human TP / Thymidine Phosphorylase
Human
IHC, Western blot, ELISA
Unconjugated
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal PE Conjugated Human IHC, WB, ELISA No Primary
Anti-TP / Thymidine Phosphorylase Antibody (PE) LS-C277042
Rabbit Polyclonal (IgG) to Human TP / Thymidine Phosphorylase
Human
IHC, Western blot, ELISA
PE Conjugated
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal AP Conjugated Human IHC, WB, ELISA No Primary
Anti-TP / Thymidine Phosphorylase Antibody (AP) LS-C277036
Rabbit Polyclonal (IgG) to Human TP / Thymidine Phosphorylase
Human
IHC, Western blot, ELISA
AP Conjugated
TP / Thymidine Phosphorylase Mouse IgG1 Monoclonal Unconjugated Human IHC, WB, IP No Primary
Anti-TP / Thymidine Phosphorylase Antibody LS-C74982
Mouse Monoclonal (IgG1) to Human TP / Thymidine Phosphorylase
Human
IHC, Western blot, Immunoprecipitation
Unconjugated
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal Biotin Conjugated Human IHC, WB, ELISA No Primary
Anti-TP / Thymidine Phosphorylase Antibody (Biotin) LS-C277039
Rabbit Polyclonal (IgG) to Human TP / Thymidine Phosphorylase
Human
IHC, Western blot, ELISA
Biotin Conjugated
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal APC Conjugated Human IHC, WB, ELISA No Primary
Anti-TP / Thymidine Phosphorylase Antibody (APC) LS-C277037
Rabbit Polyclonal (IgG) to Human TP / Thymidine Phosphorylase
Human
IHC, Western blot, ELISA
APC Conjugated
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal Unconjugated Mouse WB, ELISA aa29-305 No Primary
Anti-TP / Thymidine Phosphorylase Antibody (aa29-305) LS-C296629
WB Image
Rabbit Polyclonal (IgG) to Mouse TP / Thymidine Phosphorylase
Mouse
Western blot, ELISA
Unconjugated
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal Unconjugated Rat WB, ELISA aa33-290 No Primary
Anti-TP / Thymidine Phosphorylase Antibody (aa33-290) LS-C296626
WB Image
Rabbit Polyclonal (IgG) to Rat TP / Thymidine Phosphorylase
Rat
Western blot, ELISA
Unconjugated
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal Unconjugated Human WB, ELISA aa38-247 No Primary
Anti-TP / Thymidine Phosphorylase Antibody (aa38-247) LS-C296625
WB Image
Rabbit Polyclonal (IgG) to Human TP / Thymidine Phosphorylase
Human
Western blot, ELISA
Unconjugated
TP / Thymidine Phosphorylase Rabbit Polyclonal Unconjugated Rat, Human, Mouse WB aa89-138 No Primary
Anti-TP / Thymidine Phosphorylase Antibody (aa89-138) LS-C170199
WB Image
Rabbit Polyclonal to Rat TP / Thymidine Phosphorylase
Rat, Human, Mouse
Western blot
Unconjugated
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal FITC Conjugated Rat WB, ELISA aa33-290 No Primary
Anti-TP / Thymidine Phosphorylase Antibody (aa33-290, FITC) LS-C304533
Rabbit Polyclonal (IgG) to Rat TP / Thymidine Phosphorylase
Rat
Western blot, ELISA
FITC Conjugated
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal Biotin Conjugated Rat WB, ELISA aa33-290 No Primary
Anti-TP / Thymidine Phosphorylase Antibody (aa33-290, Biotin) LS-C298672
Rabbit Polyclonal (IgG) to Rat TP / Thymidine Phosphorylase
Rat
Western blot, ELISA
Biotin Conjugated
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal Biotin Conjugated Human WB, ELISA aa38-247 No Primary
Anti-TP / Thymidine Phosphorylase Antibody (aa38-247, Biotin) LS-C297466
Rabbit Polyclonal (IgG) to Human TP / Thymidine Phosphorylase
Human
Western blot, ELISA
Biotin Conjugated
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal FITC Conjugated Human WB aa38-247 No Primary
Anti-TP / Thymidine Phosphorylase Antibody (aa38-247, FITC) LS-C301857
Rabbit Polyclonal (IgG) to Human TP / Thymidine Phosphorylase
Human
Western blot
FITC Conjugated
TP / Thymidine Phosphorylase Rabbit IgG Monoclonal Unconjugated Human WB, IP No Primary
Anti-TP / Thymidine Phosphorylase Antibody LS-C132445
Rabbit Monoclonal (IgG) to Human TP / Thymidine Phosphorylase
Human
Western blot, Immunoprecipitation
Unconjugated
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal Unconjugated Human WB, IP No Primary
Anti-TP / Thymidine Phosphorylase Antibody LS-C310217
Rabbit Polyclonal (IgG) to Human TP / Thymidine Phosphorylase
Human
Western blot, Immunoprecipitation
Unconjugated
TP / Thymidine Phosphorylase Rabbit IgG Polyclonal Unconjugated Human WB No Primary
Anti-TP / Thymidine Phosphorylase Antibody LS-C310219
Rabbit Polyclonal (IgG) to Human TP / Thymidine Phosphorylase
Human
Western blot
Unconjugated

TP / Thymidine Phosphorylase Feature Table


Feature Type Location Details
catalytic activity 1 - 482 Thymidine + phosphate = thymine + 2-deoxy- alpha-D-ribose 1-phosphate.
Disease 1 - 482 Defects in TYMP are the cause of mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) [MIM:603041]; also known as myoneurogastrointestinal encephalomyopathy. MNGIE is an autosomal recessive disease associated with multiple deletions of skeletal muscle mitochondrial DNA (MtDNA). It is clinically characterized by onset between the second and fifth decades of life, ptosis, progressive external ophthalmoplegia, gastrointestinal dysmotility (often pseudoobstruction), diffuse leukoencephalopathy, thin body habitus, peripheral neuropathy, and myopathy.
Function 1 - 482 Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
Function 1 - 482 May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro.
pathway 1 - 482 Pyrimidine metabolism; dTMP biosynthesis via salvage pathway; dTMP from thymine: step 1/2.
Similarity 1 - 482 Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Subunit 1 - 482 Homodimer.
web resource 1 - 482 Name=GeneReviews; URL="http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/TYMP";
web resource 1 - 482 Name=R&D Systems' cytokine mini-reviews: PD-ECGF; URL="http://www.rndsystems.com/molecule_detail.aspx?m=1965";
arrayexpress 1 - 482 P19971
bgee 1 - 482 P19971
brenda 1 - 482 2.4.2.4
cleanex 1 - 482 HS_TYMP
ctd 1 - 482 1890
doi 1 - 482 10
drugbank 1 - 482 DB00322
drugbank 1 - 482 DB00544
drugbank 1 - 482 DB00675
drugbank 1 - 482 DB00795
drugbank 1 - 482 DB01101
drugbank 1 - 482 DB01248
eggnog 1 - 482 prNOG15774
embl 1 - 482 BC018160
embl 1 - 482 BC052211
embl 1 - 482 M63193
embl 1 - 482 U62317
ensembl 1 - 482 ENST00000252029
ensembl 1 - 482 ENST00000395678
ensembl 1 - 482 ENST00000395680
gene3d 1 - 482 G3DSA:1.20.970.10
gene3d 1 - 482 G3DSA:3.40.1030.10
genecards 1 - 482 GC22M050964
geneid 1 - 482 1890
genevestigator 1 - 482 P19971
germonline 1 - 482 ENSG00000025708
go 1 - 482 GO:0000002
go 1 - 482 GO:0001525
go 1 - 482 GO:0005161
go 1 - 482 GO:0006206
go 1 - 482 GO:0006213
go 1 - 482 GO:0006220
go 1 - 482 GO:0006260
go 1 - 482 GO:0006935
go 1 - 482 GO:0008083
go 1 - 482 GO:0009032
go 1 - 482 GO:0030154
h-invdb 1 - 482 HIX0016616
hgnc 1 - 482 HGNC:3148
hovergen 1 - 482 HBG000082
hpa 1 - 482 CAB002518
hpa 1 - 482 HPA001072
interpro 1 - 482 IPR000053
interpro 1 - 482 IPR000312
interpro 1 - 482 IPR013102
interpro 1 - 482 IPR017459
interpro 1 - 482 IPR017872
interpro 1 - 482 IPR018090
interpro 1 - 482 IPR020072
ipi 1 - 482 IPI00292858
kegg 1 - 482 hsa:1890
medline 1 - 482 20057165
medline 1 - 482 22167133
medline 1 - 482 89181955
medline 1 - 482 92236753
medline 1 - 482 92272724
medline 1 - 482 93015908
medline 1 - 482 99123033
mim 1 - 482 131222
mim 1 - 482 603041
nextbio 1 - 482 7707
ogp 1 - 482 P19971
orphanet 1 - 482 298
orphanet 1 - 482 35698
orthodb 1 - 482 EOG91G5Q8
panther 1 - 482 PTHR10515
pdb 1 - 482 1UOU
pdb 1 - 482 2J0F
pdb 1 - 482 2WK5
pdb 1 - 482 2WK6
pdbsum 1 - 482 1UOU
pdbsum 1 - 482 2J0F
pdbsum 1 - 482 2WK5
pdbsum 1 - 482 2WK6
pfam 1 - 482 PF00591
pfam 1 - 482 PF02885
pfam 1 - 482 PF07831
pharmgkb 1 - 482 PA153
phylomedb 1 - 482 P19971
pir 1 - 482 S03904
pirsf 1 - 482 PIRSF000478
pride 1 - 482 P19971
prosite 1 - 482 PS00647
proteinmodelportal 1 - 482 P19971
pubmed 1 - 482 10591208
pubmed 1 - 482 12177387
pubmed 1 - 482 1400349
pubmed 1 - 482 15489334
pubmed 1 - 482 1570012
pubmed 1 - 482 1580101
pubmed 1 - 482 1590793
pubmed 1 - 482 2467210
pubmed 1 - 482 9924029
reactome 1 - 482 REACT_1698
refseq 1 - 482 NP_001107227.1
refseq 1 - 482 NP_001107228.1
refseq 1 - 482 NP_001944.1
string 1 - 482 P19971
supfam 1 - 482 SSF47648
supfam 1 - 482 SSF52418
supfam 1 - 482 SSF54680
tigrfams 1 - 482 TIGR02644
ucsc 1 - 482 uc003bmb.2
unigene 1 - 482 Hs.531314
unigene 1 - 482 Hs.592212
chain 11 - 482 Thymidine phosphorylase /FTId=PRO_0000035875.
conflict 195 - 195 D -> E (in Ref. 4; AAH18160)
propep 1 - 10 /FTId=PRO_0000035874.
repeat 265 - 279 R-V-A-A-A-L-X(5,6)-L-G-R
repeat 329 - 342 R-V-A-A-A-L-X(5,6)-L-G-R
repeat 393 - 401 R-A-L-X-X-A-L-V-L
repeat 453 - 461 R-A-L-X-X-A-L-V-L
variant 44 - 44 R -> Q (in MNGIE) /FTId=VAR_016777.
variant 145 - 145 G -> R (in MNGIE) /FTId=VAR_007643.
variant 153 - 153 G -> S (in MNGIE) /FTId=VAR_007644.
variant 222 - 222 K -> R (in MNGIE) /FTId=VAR_007645.
variant 289 - 289 E -> A (in MNGIE) /FTId=VAR_007646.
variant 397 - 398 Missing (in MNGIE) /FTId=VAR_007647.
variant 471 - 471 S -> L (in dbSNP:rs11479) /FTId=VAR_007648.
keyword 1 - 482 3D-structure
keyword 1 - 482 Angiogenesis
keyword 1 - 482 Chemotaxis
keyword 1 - 482 Complete proteome
keyword 1 - 482 Developmental protein
keyword 1 - 482 Differentiation
keyword 1 - 482 Direct protein sequencing
keyword 1 - 482 Disease mutation
keyword 1 - 482 Glycosyltransferase
keyword 1 - 482 Growth factor
keyword 1 - 482 Polymorphism
keyword 1 - 482 Repeat
keyword 1 - 482 Transferase
Molecular Weight 1 - 482 49955
1 hit 1 - 482 PF00591
1 hit 1 - 482 PF02885
1 hit 1 - 482 PF07831
1 hit 1 - 482 PS00647

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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