PTBP1

polypyrimidine tract binding protein 1

PTBP1 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.

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Products

Antibodies (53)

Proteins (12)

ELISA Kits (5)

Type

Custom (3)

Over-Expression Lysate (6)

Primary (53)

Recombinant (6)

Sandwich (2)

Target

PTBP1 (70)

Reactivity

Human (54)

Mouse (21)

Rat (17)

Bat (3)

Bovine (8)

Chicken (6)

Chimpanzee (6)

Dog (3)

Gibbon (6)

Guinea pig (6)

Hamster (1)

Horse (6)

Monkey (7)

Pig (5)

Rabbit (3)

Rodent (6)

Xenopus (6)

Zebrafish (3)

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Application

IHC (13)

IHC-P (5)

WB (49)

ELISA (13)

ICC (1)

IF (14)

IP (13)

Peptide-ELISA (2)

Host

rabbit (37)

mouse (15)

goat (1)

Product Group

IHCPlus (3)

Isotype

IgG (25)

IgG1 (12)

IgG1,k (3)

Clonality

monoclonal mc (15)

polyclonal pc (38)

Clone

1D4B (1)

3H7 (1)

3H8 (1)

Format

96-Well Strip Plate (5)

APC (1)

APC Conjugated (4)

Azide-free (1)

Biotin Conjugated (7)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (7)

HRP Conjugated (7)

PE Conjugated (4)

Preservative Free (1)

Unconjugated (22)

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Epitope

aa1-531 (8)

aa26-55 (7)

C-Terminus (6)

N-Terminus (4)

aa2-14 (1)

Publications

No (70)

Sample Type

Plasma (2)

Serum (2)

Tag

GST (2)

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (8)

Species

Human (9)

Source

293T Cells (3)

E. coli (1)

HEK 293 Cells (5)

Wheat Germ Extract (3)

Purification

Purified (2)

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IHC-plus™ PTBP1 Antibody (clone 3H8) LS-B4399

(4.0) Rating

Antibody:

PTBP1 Mouse anti-Human Monoclonal (3H8) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ PTBP1 Antibody (aa2-14) LS-B3235

(4.0) Rating

Antibody:

PTBP1 Goat anti-Human Polyclonal (aa2-14) Antibody

Reactivity:

Mouse, Bovine, Rat, Hamster, Pig, Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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Human PTBP1 Protein (Recombinant His, N-Terminal) (aa1-531) - LS-G25069

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

60.9 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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PTBP1 Antibody (Preservative Free) LS-C815697

Antibody:

PTBP1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC-P, IP, WB

Format:

Unconjugated, Preservative Free

Price:

20 µl/$271; 100 µl/$412

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PTBP1 Antibody (C-Terminus) LS-C38296

Antibody:

PTBP1 Mouse anti-Human Monoclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat, Rodent, Human

Applications:

IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$842

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PTBP1 Antibody (HRP) LS-C548861

Antibody:

PTBP1 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Mouse, Rat, Rodent, Human

Applications:

IF, IP, WB

Format:

HRP Conjugated

Price:

100 µl/$1,063

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PTBP1 Antibody (Biotin) LS-C528770

Antibody:

PTBP1 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Mouse, Rat, Rodent, Human

Applications:

IF, IP, WB

Format:

Biotin Conjugated

Price:

100 µl/$1,063

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PTBP1 Antibody (FITC) LS-C538715

Antibody:

PTBP1 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Mouse, Rat, Rodent, Human

Applications:

IF, IP, WB

Format:

FITC Conjugated

Price:

100 µl/$1,063

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PTBP1 Antibody (APC) LS-C518783

Antibody:

PTBP1 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Mouse, Rat, Rodent, Human

Applications:

IF, IP, WB

Format:

APC Conjugated

Price:

100 µl/$1,063

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PTBP1 Antibody (PE) LS-C656869

Antibody:

PTBP1 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Mouse, Rat, Rodent, Human

Applications:

IF, IP, WB

Format:

PE Conjugated

Price:

100 µl/$1,063

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

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IHC-plus™ PTBP1 Antibody LS-B13371

(4.0) Rating

Antibody:

PTBP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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Human PTBP1 (Sandwich ELISA) ELISA Kit - LS-F49653

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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PTBP1 Antibody LS-C408906

Antibody:

PTBP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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PTBP1 Antibody (C-Terminus) LS-C38295

Antibody:

PTBP1 Mouse anti-Human Monoclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$890

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PTBP1 Antibody (HRP) LS-C548858

Antibody:

PTBP1 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

IF, IP, WB

Format:

HRP Conjugated

Price:

100 µl/$1,104

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PTBP1 Antibody (Biotin) LS-C528771

Antibody:

PTBP1 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

IF, IP, WB

Format:

Biotin Conjugated

Price:

100 µl/$1,104

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PTBP1 Antibody (FITC) LS-C538714

Antibody:

PTBP1 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

IF, IP, WB

Format:

FITC Conjugated

Price:

100 µl/$1,104

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PTBP1 Antibody (APC) LS-C518782

Antibody:

PTBP1 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

IF, IP, WB

Format:

APC Conjugated

Price:

100 µl/$1,104

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PTBP1 Antibody (PE) LS-C656868

Antibody:

PTBP1 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

IF, IP, WB

Format:

PE Conjugated

Price:

100 µl/$1,104

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

PTBP1 Antibody LS-C751679

Antibody:

PTBP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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PTBP1 Antibody LS-C751680

Antibody:

PTBP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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PTBP1 Antibody LS-C806259

Antibody:

PTBP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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PTBP1 Antibody (clone 1D4B) LS-C189751

Antibody:

PTBP1 Mouse anti-Human Monoclonal (1D4B) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

25 µg/$459

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PTBP1 Antibody LS-C667971

Antibody:

PTBP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

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PTBP1 Antibody (clone 3H7) LS-C783567

Antibody:

PTBP1 Mouse anti-Human Monoclonal (3H7) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

25 µg/$276

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