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Unfortunately, the antibody LS-C163660 is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



PDK1 / PDPK1 Antibodies

3-phosphoinositide dependent protein kinase-1

Gene Name: 3-phosphoinositide dependent protein kinase-1
Family/Subfamily: Protein Kinase , RAC/AKT
Synonyms: PDPK1 Antibody, HPDK1 Antibody, PkB kinase like gene 1 Antibody, PkB-like 1 Antibody, Pdk-1 Antibody, PkB kinase Antibody, PRO0461 Antibody
Target Sequences: NM_002613 NP_002604.1 O15530
 PDK1 / PDPK1 Feature Table
Featured Image

Featured PDK1 / PDPK1 Antibody

LS-B6365 is a rabbit polyclonal antibody that LifeSpan has tested extensively in immunohistochemistry (IHC) and is an excellent antibody for use in formalin-fixed paraffin embedded tissues. Multiple tissues were immunolabeled and the results were interpreted by a LifeSpan pathologist. This image shows an example of staining in formalin-fixed paraffin embedded tissue. Learn more about our IHC Validation procedure. All LSBio antibodies are 100% guaranteed.

Publications (1)

1
Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II: role in mesangial cell hypertrophy and fibronectin expression. Block K, Eid A, Griendling KK, Lee DY, Wittrant Y, Gorin Y. The Journal of biological chemistry. 2008 283:24061-76. (WB) [PubMed:18559349] [PMC:PMC2527116] Related Antibodies: LS-C49859.

PDK1 / PDPK1 Antibodies (38)

Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
PDK1 / PDPK1 Rabbit IgG Polyclonal Unconjugated Human IHC-P, WB, ELISA No Primary
Anti-PDK1 / PDPK1 Antibody IHC-plus™ LS-B6365
IHC Image
WB Image
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
PDK1 / PDPK1 Rabbit Polyclonal Unconjugated Human IHC-P, ELISA pSer241 No Primary
Anti-PDK1 / PDPK1 Antibody (phospho-Ser241) IHC-plus™ LS-B859
IHC Image
Rabbit Polyclonal to Human PDK1 / PDPK1
Human
IHC - Paraffin, ELISA
Unconjugated
PDK1 / PDPK1 Rabbit Monoclonal EPR336(2) Unconjugated Human IHC-P, ICC, WB, IP pSer241 No Primary
Anti-PDK1 / PDPK1 Antibody (phospho-Ser241, clone EPR336(2)) LS-C137777
IHC Image
WB Image
Rabbit Monoclonal [clone EPR336(2)] to Human PDK1 / PDPK1
Human
IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC-P, WB, ELISA aa210-259 No Primary
Anti-PDK1 / PDPK1 Antibody (aa210-259) LS-C118223
WB Image
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human, Mouse, Rat
IHC - Paraffin, Western blot, ELISA
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC-P, WB, ELISA pSer241 No Primary
Anti-PDK1 / PDPK1 Antibody (phospho-Ser241) LS-C117457
WB Image
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human, Mouse, Rat
IHC - Paraffin, Western blot, ELISA
Unconjugated
PDK1 / PDPK1 Rabbit Monoclonal EPR245 Unconjugated Human, Mouse, Rat IHC-P, ICC, WB N-Terminus No Primary
Anti-PDK1 / PDPK1 Antibody (N-Terminus, clone EPR245) LS-C138170
IHC Image
WB Image
Rabbit Monoclonal [clone EPR245] to Human PDK1 / PDPK1
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot
Unconjugated
PDK1 / PDPK1 Rabbit IgG Monoclonal EP569Y Unconjugated Human, Mouse, Rat IHC, WB pTyr373/Tyr376 Yes Primary
Anti-PDK1 / PDPK1 Antibody (phospho-Tyr373/Tyr376, clone EP569Y) LS-C49859
PublicationsPublications (1)
IHC Image
WB Image
Rabbit Monoclonal [clone EP569Y] (IgG) to Human PDK1 / PDPK1
Human, Mouse, Rat
IHC, Western blot
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, ELISA pTyr9 No Primary
Anti-PDK1 / PDPK1 Antibody (phospho-Tyr9) LS-C199426
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human, Mouse, Rat
IHC, ELISA
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Unconjugated Human IHC-P No Primary
Anti-PDK1 / PDPK1 Antibody LS-C210534
IHC Image
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human
IHC - Paraffin
Unconjugated
PDK1 / PDPK1 Rabbit Polyclonal Unconjugated Human, Mouse, Rat IHC, WB, IP C-Terminus No Primary
Anti-PDK1 / PDPK1 Antibody (C-Terminus) LS-C48430
WB Image
Rabbit Polyclonal to Human PDK1 / PDPK1
Human, Mouse, Rat
IHC, Western blot, Immunoprecipitation
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Unconjugated Human, Monkey, Mouse, Rat, Bovine, Dog, Pig, Rabbit, Chicken, Xenopus, Zebrafish IHC, IF, WB No Primary
Anti-PDK1 / PDPK1 Antibody LS-C124359
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human, Monkey, Mouse, Rat, Bovine, Dog, Pig, Rabbit, Chicken, Xenopus, Zebrafish
IHC, Immunofluorescence, Western blot
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, WB pSer241 No Primary
Anti-PDK1 / PDPK1 Antibody (phospho-Ser241) LS-C124358
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot
Unconjugated
PDK1 / PDPK1 Mouse IgG2a,k Monoclonal 2E2 Unconjugated Human, Rat WB, ELISA No Primary
Anti-PDK1 / PDPK1 Antibody (clone 2E2) LS-C197870
WB Image
WB Image
Mouse Monoclonal [clone 2E2] (IgG2a,k) to Human PDK1 / PDPK1
Human, Rat
Western blot, ELISA
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Unconjugated Human WB, ELISA aa83-338 No Primary
Anti-PDK1 / PDPK1 Antibody (aa83-338) LS-C295896
WB Image
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human
Western blot, ELISA
Unconjugated
PDK1 / PDPK1 Rabbit Polyclonal Unconjugated Rabbit, Human WB, ELISA aa301-312 No Primary
Anti-PDK1 / PDPK1 Antibody (aa301-312) LS-C18965
WB Image
Rabbit Polyclonal to Rabbit PDK1 / PDPK1
Rabbit, Human
Western blot, ELISA
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Unconjugated Human, Orangutan, Mouse, Guinea pig WB, IP aa506-556 No Primary
Anti-PDK1 / PDPK1 Antibody (aa506-556) LS-C288889
WB Image
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human, Orangutan, Mouse, Guinea pig
Western blot, Immunoprecipitation
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat WB, ELISA aa1-50 No Primary
Anti-PDK1 / PDPK1 Antibody (aa1-50) LS-C199425
WB Image
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human, Mouse, Rat
Western blot, ELISA
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat WB, ELISA aa2-51 No Primary
Anti-PDK1 / PDPK1 Antibody (aa2-51) LS-C200470
WB Image
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human, Mouse, Rat
Western blot, ELISA
Unconjugated
PDK1 / PDPK1 Mouse IgM,k Monoclonal Unconjugated Human WB No Primary
Anti-PDK1 / PDPK1 Antibody LS-C163498
WB Image
Mouse Monoclonal (IgM,k) to Human PDK1 / PDPK1
Human
Western blot
Unconjugated
PDK1 / PDPK1 Mouse IgM Monoclonal Unconjugated Human WB No Primary
Anti-PDK1 / PDPK1 Antibody LS-C163499
WB Image
Mouse Monoclonal (IgM) to Human PDK1 / PDPK1
Human
Western blot
Unconjugated
PDK1 / PDPK1 Rabbit IgG Monoclonal EPR6157 Unconjugated Human, Mouse, Rat WB pSer410 No Primary
Anti-PDK1 / PDPK1 Antibody (phospho-Ser410, clone EPR6157) LS-C152464
WB Image
Rabbit Monoclonal [clone EPR6157] (IgG) to Human PDK1 / PDPK1
Human, Mouse, Rat
Western blot
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Unconjugated Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Pig, Zebrafish WB aa201-250 No Primary
Anti-PDK1 / PDPK1 Antibody (aa201-250) LS-C30530
WB Image
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Pig, Zebrafish
Western blot
Unconjugated
PDK1 / PDPK1 Rabbit Polyclonal Unconjugated Human DB pSer396 No Primary
Anti-PDK1 / PDPK1 Antibody (phospho-Ser396) LS-C96792
DB Image
Rabbit Polyclonal to Human PDK1 / PDPK1
Human
Dot Blot
Unconjugated
PDK1 / PDPK1 Rabbit Polyclonal Unconjugated Arabidopsis thaliana, Arabidopsis WB, ELISA No Primary
Anti-PDK1 / PDPK1 Antibody LS-C285825
Rabbit Polyclonal to Arabidopsis thaliana PDK1 / PDPK1
Arabidopsis thaliana, Arabidopsis
Western blot, ELISA
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Biotin Conjugated Human WB, ELISA aa83-338 No Primary
Anti-PDK1 / PDPK1 Antibody (aa83-338, Biotin) LS-C298339
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human
Western blot, ELISA
Biotin Conjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal FITC Conjugated Human WB aa83-338 No Primary
Anti-PDK1 / PDPK1 Antibody (aa83-338, FITC) LS-C304860
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human
Western blot
FITC Conjugated
PDK1 / PDPK1 Mouse IgG2a Monoclonal Unconjugated WB, IP, ELISA pSer/Thr No Primary
Anti-PDK1 / PDPK1 Antibody (phospho-Ser/Thr) LS-C9552
Mouse Monoclonal (IgG2a)
Western blot, Immunoprecipitation, ELISA
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal HRP Conjugated, Azide-free Human ELISA, DB Ser396 No Primary
Anti-PDK1 / PDPK1 Antibody (Ser396, Azide-free, HRP) LS-C280679
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human
ELISA, Dot Blot
HRP Conjugated, Azide-free
PDK1 / PDPK1 Rabbit IgG Polyclonal FITC Conjugated Human ELISA, DB Ser396 No Primary
Anti-PDK1 / PDPK1 Antibody (Ser396, FITC) LS-C280678
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human
ELISA, Dot Blot
FITC Conjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal PE Conjugated Human ELISA, DB Ser396 No Primary
Anti-PDK1 / PDPK1 Antibody (Ser396, PE) LS-C280680
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human
ELISA, Dot Blot
PE Conjugated
PDK1 / PDPK1 Mouse IgG1,k Monoclonal Unconjugated Human WB, ELISA aa29-436 No Primary
Anti-PDK1 / PDPK1 Antibody (aa29-436) LS-C131339
Mouse Monoclonal (IgG1,k) to Human PDK1 / PDPK1
Human
Western blot, ELISA
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal APC Conjugated Human ELISA, DB Ser396 No Primary
Anti-PDK1 / PDPK1 Antibody (Ser396, APC) LS-C280717
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human
ELISA, Dot Blot
APC Conjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Unconjugated Human WB, ELISA C-Terminus No Primary
Anti-PDK1 / PDPK1 Antibody (C-Terminus) LS-C9549
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human
Western blot, ELISA
Unconjugated
PDK1 / PDPK1 Rabbit Polyclonal Unconjugated Human, Gorilla, Monkey WB, ELISA aa301-312 No Primary
Anti-PDK1 / PDPK1 Antibody (aa301-312) LS-C9553
Rabbit Polyclonal to Human PDK1 / PDPK1
Human, Gorilla, Monkey
Western blot, ELISA
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Unconjugated Human ELISA, DB pSer396 No
Anti-PDK1 / PDPK1 Antibody (phospho-Ser396) LS-C330579
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human
ELISA, Dot Blot
Unconjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Biotin Conjugated Human ELISA, DB Ser396 No Primary
Anti-PDK1 / PDPK1 Antibody (Ser396, Biotin) LS-C280677
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human
ELISA, Dot Blot
Biotin Conjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal AP Conjugated Human ELISA, DB Ser396 No Primary
Anti-PDK1 / PDPK1 Antibody (Ser396, AP) LS-C280676
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human
ELISA, Dot Blot
AP Conjugated
PDK1 / PDPK1 Rabbit IgG Polyclonal Unconjugated Human WB No Primary
Anti-PDK1 / PDPK1 Antibody LS-C9547
Rabbit Polyclonal (IgG) to Human PDK1 / PDPK1
Human
Western blot
Unconjugated

PDK1 / PDPK1 Feature Table


Feature Type Location Details
alternative products 1 - 556 Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=O15530-1; Sequence=Displayed; Name=2; IsoId=O15530-2; Sequence=VSP_004894; Name=3; IsoId=O15530-3; Sequence=VSP_004895;
catalytic activity 1 - 556 ATP + a protein = ADP + a phosphoprotein.
Function 1 - 556 Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.
interaction 1 - 556 Q05209:PTPN12; NbExp=1; IntAct=EBI-717097, EBI-2266035; Q9Y2R2:PTPN22; NbExp=1; IntAct=EBI-717097, EBI-1211241; P23467:PTPRB; NbExp=1; IntAct=EBI-717097, EBI-1265766; P08575:PTPRC; NbExp=1; IntAct=EBI-717097, EBI-1341; P23470:PTPRG; NbExp=1; IntAct=EBI-717097, EBI-2258115; Q12913:PTPRJ; NbExp=1; IntAct=EBI-717097, EBI-2264500; Q15262:PTPRK; NbExp=1; IntAct=EBI-717097, EBI-474052; Q16827:PTPRO; NbExp=1; IntAct=EBI-717097, EBI-723739; O00141:SGK1; NbExp=1; IntAct=EBI-717097, EBI-1042854;
ptm 1 - 556 Phosphorylated on tyrosine and serine/threonine. Phosphorylation on Ser-241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser-241, leading to its own activation.
Similarity 1 - 556 Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDK1 subfamily.
Similarity 1 - 556 Contains 1 PH domain.
Similarity 1 - 556 Contains 1 protein kinase domain.
Subcellular Location 1 - 556 Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation leading to its translocation. Tyrosine phosphorylation seems to occur only at the plasma membrane.
Subunit 1 - 556 Interacts with NPRL2.
Tissue Specificity 1 - 556 Appears to be expressed ubiquitously.
arrayexpress 1 - 556 O15530
bgee 1 - 556 O15530
brenda 1 - 556 2.7.11.1
cleanex 1 - 556 HS_PDK1
cleanex 1 - 556 HS_PDPK1
ctd 1 - 556 5170
doi 1 - 556 10
drugbank 1 - 556 DB00482
eggnog 1 - 556 prNOG14283
embl 1 - 556 AF017995
embl 1 - 556 BC012103
embl 1 - 556 CR536517
embl 1 - 556 Y15056
ensembl 1 - 556 ENST00000342085
gene3d 1 - 556 G3DSA:2.30.29.30
genecards 1 - 556 GC16P002527
geneid 1 - 556 5170
genevestigator 1 - 556 O15530
germonline 1 - 556 ENSG00000140992
go 1 - 556 GO:0004676
go 1 - 556 GO:0005524
go 1 - 556 GO:0005829
go 1 - 556 GO:0005886
go 1 - 556 GO:0006469
go 1 - 556 GO:0018107
go 1 - 556 GO:0023034
go 1 - 556 GO:0030036
go 1 - 556 GO:0032148
go 1 - 556 GO:0032869
go 1 - 556 GO:0090004
hgnc 1 - 556 HGNC:8816
hogenom 1 - 556 HBG755340
hovergen 1 - 556 HBG098357
hpa 1 - 556 CAB004272
inparanoid 1 - 556 O15530
intact 1 - 556 O15530
interpro 1 - 556 IPR000719
interpro 1 - 556 IPR002290
interpro 1 - 556 IPR008271
interpro 1 - 556 IPR011009
interpro 1 - 556 IPR011993
interpro 1 - 556 IPR015746
interpro 1 - 556 IPR017441
interpro 1 - 556 IPR017442
ipi 1 - 556 IPI00002538
ipi 1 - 556 IPI00216646
ipi 1 - 556 IPI00216647
kegg 1 - 556 hsa:5170
medline 1 - 556 21463095
medline 1 - 556 97250749
medline 1 - 556 98035195
medline 1 - 556 98111410
medline 1 - 556 98301766
medline 1 - 556 99292684
medline 1 - 556 99386657
mim 1 - 556 605213
mint 1 - 556 MINT-203926
nextbio 1 - 556 20004
oma 1 - 556 HLQTPPK
orthodb 1 - 556 EOG9Z390V
panther 1 - 556 PTHR22985:SF93
pathway_interaction_db 1 - 556 bcr_5pathway
pathway_interaction_db 1 - 556 cd8tcrpathway
pathway_interaction_db 1 - 556 fgf_pathway
pathway_interaction_db 1 - 556 igf1_pathway
pathway_interaction_db 1 - 556 insulin_pathway
pathway_interaction_db 1 - 556 kitpathway
pathway_interaction_db 1 - 556 met_pathway
pathway_interaction_db 1 - 556 mtor_4pathway
pathway_interaction_db 1 - 556 pi3kciaktpathway
pathway_interaction_db 1 - 556 pi3kcipathway
pathway_interaction_db 1 - 556 pi3kplctrkpathway
pathway_interaction_db 1 - 556 tcrpathway
pathway_interaction_db 1 - 556 tgfbrpathway
pathway_interaction_db 1 - 556 vegfr1_2_pathway
pathway_interaction_db 1 - 556 vegfr1_pathway
pdb 1 - 556 1H1W
pdb 1 - 556 1OKY
pdb 1 - 556 1OKZ
pdb 1 - 556 1UU3
pdb 1 - 556 1UU7
pdb 1 - 556 1UU8
pdb 1 - 556 1UU9
pdb 1 - 556 1UVR
pdb 1 - 556 1W1D
pdb 1 - 556 1W1G
pdb 1 - 556 1W1H
pdb 1 - 556 1Z5M
pdb 1 - 556 2BIY
pdb 1 - 556 2PE0
pdb 1 - 556 2PE1
pdb 1 - 556 2PE2
pdb 1 - 556 2R7B
pdb 1 - 556 2VKI
pdb 1 - 556 3H9O
pdb 1 - 556 3HRC
pdb 1 - 556 3HRF
pdb 1 - 556 3ION
pdb 1 - 556 3IOP
pdbsum 1 - 556 1H1W
pdbsum 1 - 556 1OKY
pdbsum 1 - 556 1OKZ
pdbsum 1 - 556 1UU3
pdbsum 1 - 556 1UU7
pdbsum 1 - 556 1UU8
pdbsum 1 - 556 1UU9
pdbsum 1 - 556 1UVR
pdbsum 1 - 556 1W1D
pdbsum 1 - 556 1W1G
pdbsum 1 - 556 1W1H
pdbsum 1 - 556 1Z5M
pdbsum 1 - 556 2BIY
pdbsum 1 - 556 2PE0
pdbsum 1 - 556 2PE1
pdbsum 1 - 556 2PE2
pdbsum 1 - 556 2R7B
pdbsum 1 - 556 2VKI
pdbsum 1 - 556 3H9O
pdbsum 1 - 556 3HRC
pdbsum 1 - 556 3HRF
pdbsum 1 - 556 3ION
pdbsum 1 - 556 3IOP
pfam 1 - 556 PF00069
pharmgkb 1 - 556 PA33160
phosphosite 1 - 556 O15530
phylomedb 1 - 556 O15530
pride 1 - 556 O15530
prosite 1 - 556 PS00107
prosite 1 - 556 PS00108
prosite 1 - 556 PS50003
prosite 1 - 556 PS50011
proteinmodelportal 1 - 556 O15530
pubmed 1 - 556 10364160
pubmed 1 - 556 10455013
pubmed 1 - 556 11481331
pubmed 1 - 556 15302935
pubmed 1 - 556 15489334
pubmed 1 - 556 16807684
pubmed 1 - 556 17081983
pubmed 1 - 556 18616680
pubmed 1 - 556 18669648
pubmed 1 - 556 18691976
pubmed 1 - 556 19369195
pubmed 1 - 556 19413330
pubmed 1 - 556 19608861
pubmed 1 - 556 19690332
pubmed 1 - 556 9094314
pubmed 1 - 556 9368760
pubmed 1 - 556 9445477
pubmed 1 - 556 9637919
reactome 1 - 556 REACT_11061
reactome 1 - 556 REACT_13685
reactome 1 - 556 REACT_14797
reactome 1 - 556 REACT_498
reactome 1 - 556 REACT_604
reactome 1 - 556 REACT_6900
refseq 1 - 556 NP_002604.1
refseq 1 - 556 NP_112558.2
smart 1 - 556 SM00220
string 1 - 556 O15530
supfam 1 - 556 SSF56112
ucsc 1 - 556 uc002cqs.1
unigene 1 - 556 Hs.459691
act_site 205 - 205 Proton acceptor (By similarity)
binding 111 - 111 ATP (By similarity)
chain 1 - 556 3-phosphoinositide-dependent protein kinase 1. /FTId=PRO_0000086500.
compbias 389 - 398 Poly-Ser
domain 82 - 342 Protein kinase
domain 459 - 550 PH
Modification 9 - 9 Phosphotyrosine
Modification 25 - 25 Phosphoserine
Modification 35 - 35 Phosphoserine
Modification 37 - 37 Phosphothreonine
Modification 241 - 241 Phosphoserine; by autocatalysis
Modification 245 - 245 Phosphothreonine
Modification 304 - 304 N6-acetyllysine
Modification 373 - 373 Phosphotyrosine
Modification 376 - 376 Phosphotyrosine
Modification 393 - 393 Phosphoserine
Modification 396 - 396 Phosphoserine
Modification 410 - 410 Phosphoserine
mutagen 9 - 9 Y->F: Slight reduction in pervanadate- stimulated tyrosine phosphorylation.
mutagen 25 - 25 S->A: No effect
mutagen 241 - 241 S->A: No activation
mutagen 277 - 277 A->V: 3-fold increase in kinase activity
mutagen 373 - 373 Y->F: Reduction in basal activity
mutagen 376 - 376 Y->F: Reduction in basal activity
mutagen 393 - 393 S->A: No effect
mutagen 396 - 396 S->A: No effect
mutagen 410 - 410 S->A: No effect
mutagen 474 - 474 R->A: No PDGF-dependent translocation to the membrane.
np_bind 88 - 96 ATP (By similarity)
var_seq 1 - 50 Missing (in isoform 2) /FTId=VSP_004894.
var_seq 238 - 263 Missing (in isoform 3) /FTId=VSP_004895.
keyword 1 - 556 3D-structure
keyword 1 - 556 Acetylation
keyword 1 - 556 Alternative splicing
keyword 1 - 556 ATP-binding
keyword 1 - 556 Complete proteome
keyword 1 - 556 Cytoplasm
keyword 1 - 556 Direct protein sequencing
keyword 1 - 556 Kinase
keyword 1 - 556 Membrane
keyword 1 - 556 Nucleotide-binding
keyword 1 - 556 Phosphoprotein
keyword 1 - 556 Serine/threonine-protein kinase
keyword 1 - 556 Transferase
Molecular Weight 1 - 556 63152
1 hit 1 - 556 PF00069
1 hit 1 - 556 PS00107
1 hit 1 - 556 PS00108
1 hit 1 - 556 PS50011
false_neg 1 - 556 PS50003

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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