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IL25 / IL17E
interleukin 25
The IL17 proteins are a family of potent cytokines that act to induce proinflammatory responses. Studies have shown that IL17E binds strongly to IL17RB. Receptor binding of ligand has been shown to lead to the activation of nuclear factor kappa-B and production of IL8. Exposure of mice to IL17 resulted in a Th-2 like response characterized by increased serum IgE, IgG1 and IgA levels, blood eosinophilia, increased lymphocytes and neutrophils, and pathological changes in the tissues that included eosinophilic infiltrates, increased mucus production, B-lymphocyte hyperplasia and epithelial cell hyperplasia/hypertrophy.
| Gene Name: | interleukin 25 |
| Family/Subfamily: | Interleukin |
| Synonyms: | IL25, Interleukin 17E, Interleukin 25, Interleukin-25, IL17E, IL-17E, IL-25, Interleukin-17E |
| Target Sequences: | NM_022789 NP_073626.1 Q9H293 |
Publications (3)
1
Interleukin-25: a cytokine linking eosinophils and adaptive immunity in Churg-Strauss syndrome. Terrier B, Bièche I, Maisonobe T, Laurendeau I, Rosenzwajg M, Kahn JE, Diemert MC, Musset L, Vidaud M, Sène D, Costedoat-Chalumeau N, Le Thi-Huong D, Amoura Z, Klatzmann D, Cacoub P, Saadoun D. Blood. 2010 116:4523-31. (WB; Human)
[Full Text Article]
[PubMed:20729468]
Related Antibodies: LS-B123.
2
Elevations in Th2-initiating cytokines (IL-33, IL-25, TSLP) in lesional skin from Chronic Spontaneous ("Idiopathic") Urticaria. Clark P, Maurer M, Ying S. The British journal of dermatology. Dec; [Full Text Article]
[PubMed:25523947]
Related Antibodies: LS-C165200.
3
Bronchial Allergen Challenge of Patients with Atopic Asthma Triggers an Alarmin (IL-33, TSLP, and IL-25) Response in the Airways Epithelium and Submucosa. Wang W, Li Y, Lv Z, Chen Y, Li Y, Huang K, Corrigan CJ, Ying S. Journal of immunology (Baltimore, Md. : 1950). 2018 October;201:2221-2231. [Full Text Article]
[PubMed:30185520]
Related Antibodies: LS-C165200.
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IL25 / IL17E Mouse anti-Human Monoclonal (aa115-132) (68C1039.2) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
IL25 / IL17E Rabbit anti-Human Polyclonal (aa76-104) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
IL25 / IL17E Mouse anti-Human Monoclonal (aa115-132) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$717
IL25 / IL17E Rat anti-Mouse Monoclonal (PE) Antibody
Mouse
Flo
PE Conjugated
100 Tests/$832
IL25 / IL17E Mouse anti-Human Monoclonal (PE) Antibody
Human
Flo
PE Conjugated
100 Tests/$820
Sandwich
12 x 8-Well Microstrips
Human
32 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$479
IL25 / IL17E Rabbit anti-Mouse Monoclonal (110) Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
IL25 / IL17E Mouse anti-Human Monoclonal (APC) Antibody
Human
Flo
APC Conjugated
100 Tests/$865
Sandwich
96-Well Microplate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Development Kit
200 Wells
Human
32 - 2000 pg/ml
Colorimetric - 405nm (ABTS)
1 Test/$180
Sandwich
96-Well Strip Plate
Human
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$798
IL25 / IL17E Mouse anti-Human Monoclonal (8B1) Antibody
Human
Flo, WB
Unconjugated
100 µg/$386
IL25 / IL17E Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
IL25 / IL17E Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
IL25 / IL17E Mouse anti-Human Monoclonal (SB129e) Antibody
Human
ELISA
Unconjugated
0.5 mg/$448
IL25 / IL17E Mouse anti-Human Monoclonal (SB129a) Antibody
Human
ELISA
Unconjugated
0.5 mg/$448
IL25 / IL17E Rabbit anti-Rat Polyclonal (aa33-169) Antibody
Rat
WB
Unconjugated
100 µl/$312; 200 µl/$355; 500 µl/$500; 1 ml/$573; 2 ml/$780; 5 ml/$1,268
IL25 / IL17E Rabbit anti-Human Polyclonal (aa33-177) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$460
Development Kit
200 Wells
Human
16 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Test/$180
Sandwich
96-Well Microplate
Human
0.41 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
Fast Shipping
IL25 / IL17E Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
IL25 / IL17E Mouse anti-Human Monoclonal (11K8B1) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$574
IL25 / IL17E Rabbit anti-Human Polyclonal (aa76-104) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
IL25 / IL17E Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
IL25 / IL17E Mouse anti-Human Monoclonal (11K8B1) Antibody
Human
ELISA, Flo, WB
Unconjugated
25 µl/$304
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