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Unfortunately, the antibody LS-B3057 is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



CHI3L1 / YKL-40 Antibodies

chitinase 3-like 1 (cartilage glycoprotein-39)

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. Chitinase 3-like 1 (cartilage glycoprotein-39, CHI3L1) is a glycoprotein member of the glycosyl hydrolase 18 family. CHI3L1 lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. CHI3L1 is thought to play a role in the process of inflammation and tissue remodeling.

Gene Name: chitinase 3-like 1 (cartilage glycoprotein-39)
Synonyms: CHI3L1 Antibody, 39 kDa synovial protein Antibody, ASRT7 Antibody, Cartilage glycoprotein 39 Antibody, CGP-39 Antibody, Chitinase-3-like protein 1 Antibody, gp39 Antibody, HCGP-39 Antibody, HCGP-3P Antibody, GP-39 Antibody, HC-gp39 Antibody, YKL40 Antibody, YYL-40 Antibody, YKL-40 Antibody
Target Sequences: NM_001276 NP_001267.2 P36222
 CHI3L1 / YKL-40 Feature Table
Featured Image

Featured CHI3L1 / YKL-40 Antibody

LS-B8213 is a rabbit polyclonal antibody that LifeSpan has tested extensively in immunohistochemistry (IHC) and is an excellent antibody for use in formalin-fixed paraffin embedded tissues. Multiple tissues were immunolabeled and the results were interpreted by a LifeSpan pathologist. This image shows an example of staining in formalin-fixed paraffin embedded tissue. Learn more about our IHC Validation procedure. All LSBio antibodies are 100% guaranteed.


CHI3L1 / YKL-40 Antibodies (8)

Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
CHI3L1 / YKL-40 Rabbit IgG Polyclonal Unconjugated Human, Chimpanzee, Orangutan, Gibbon, Monkey, Rat, Rabbit IHC-P, WB aa198-247 No Primary
Anti-CHI3L1 / YKL-40 Antibody (aa198-247) IHC-plus™ LS-B8213
IHC Image
WB Image
Rabbit Polyclonal (IgG) to Human CHI3L1 / YKL-40
Human, Chimpanzee, Orangutan, Gibbon, Monkey, Rat, Rabbit
IHC - Paraffin, Western blot
Unconjugated
CHI3L1 / YKL-40 Rabbit IgG Polyclonal FITC Conjugated Human IHC, WB, Flo, ELISA aa314-344 No Primary
Anti-CHI3L1 / YKL-40 Antibody (aa314-344, FITC) LS-C254735
Rabbit Polyclonal (IgG) to Human CHI3L1 / YKL-40
Human
IHC, Western blot, Flow Cytometry, ELISA
FITC Conjugated
CHI3L1 / YKL-40 Rabbit IgG Polyclonal HRP Conjugated, Azide-free Human IHC, WB, Flo, ELISA aa314-344 No Primary
Anti-CHI3L1 / YKL-40 Antibody (aa314-344, Azide-free, HRP) LS-C254737
Rabbit Polyclonal (IgG) to Human CHI3L1 / YKL-40
Human
IHC, Western blot, Flow Cytometry, ELISA
HRP Conjugated, Azide-free
CHI3L1 / YKL-40 Rabbit IgG Polyclonal Biotin Conjugated Human IHC, WB, Flo, ELISA aa314-344 No Primary
Anti-CHI3L1 / YKL-40 Antibody (aa314-344, Biotin) LS-C254734
Rabbit Polyclonal (IgG) to Human CHI3L1 / YKL-40
Human
IHC, Western blot, Flow Cytometry, ELISA
Biotin Conjugated
CHI3L1 / YKL-40 Rabbit IgG Polyclonal AP Conjugated Human IHC, WB, Flo, ELISA aa314-344 No Primary
Anti-CHI3L1 / YKL-40 Antibody (aa314-344, AP) LS-C254732
Rabbit Polyclonal (IgG) to Human CHI3L1 / YKL-40
Human
IHC, Western blot, Flow Cytometry, ELISA
AP Conjugated
CHI3L1 / YKL-40 Rabbit IgG Polyclonal APC Conjugated Human IHC, WB, Flo, ELISA aa314-344 No Primary
Anti-CHI3L1 / YKL-40 Antibody (aa314-344, APC) LS-C254733
Rabbit Polyclonal (IgG) to Human CHI3L1 / YKL-40
Human
IHC, Western blot, Flow Cytometry, ELISA
APC Conjugated
CHI3L1 / YKL-40 Mouse IgG2b,k Monoclonal PAT4A3AT Unconjugated Human WB, ELISA aa22-383 No Primary
Anti-CHI3L1 / YKL-40 Antibody (aa22-383, clone PAT4A3AT) LS-C204807
Mouse Monoclonal [clone PAT4A3AT] (IgG2b,k) to Human CHI3L1 / YKL-40
Human
Western blot, ELISA
Unconjugated
CHI3L1 / YKL-40 Mouse IgG2b,k Monoclonal Unconjugated Human WB, ELISA aa22-383 No Primary
Anti-CHI3L1 / YKL-40 Antibody (aa22-383) LS-C125352
Mouse Monoclonal (IgG2b,k) to Human CHI3L1 / YKL-40
Human
Western blot, ELISA
Unconjugated

CHI3L1 / YKL-40 Feature Table


Feature Type Location Details
Disease 1 - 383 A genetic variation in CHI3L1 is associated with susceptibility to asthma-related traits type 7 (ASRT7) [MIM:611960]. Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing and dyspnea, bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis.
Function 1 - 383 Carbohydrate-binding lectin with a preference for chitin. May play a role in defense against pathogens, or in tissue remodeling. May play an important role in the capacity of cells to respond to and cope with changes in their environment.
ptm 1 - 383 Glycosylated.
Similarity 1 - 383 Belongs to the glycosyl hydrolase 18 family.
Subcellular Location 1 - 383 Secreted, extracellular space.
Subunit 1 - 383 Monomer.
Tissue Specificity 1 - 383 Present in activated macrophages, articular chondrocytes, synovial cells as well as in liver. Undetectable in muscle tissues, lung, pancreas, mononuclear cells, or fibroblasts.
arrayexpress 1 - 383 P36222
bgee 1 - 383 P36222
cazy 1 - 383 GH18
cleanex 1 - 383 HS_CHI3L1
ctd 1 - 383 1116
doi 1 - 383 10
eggnog 1 - 383 prNOG13745
embl 1 - 383 AK312911
embl 1 - 383 BC008568
embl 1 - 383 BC038354
embl 1 - 383 BC039132
embl 1 - 383 BT007223
embl 1 - 383 CH471067
embl 1 - 383 M80927
embl 1 - 383 Y08374
embl 1 - 383 Y08375
embl 1 - 383 Y08376
embl 1 - 383 Y08377
embl 1 - 383 Y08378
ensembl 1 - 383 ENST00000255409
gene3d 1 - 383 G3DSA:3.20.20.80
genecards 1 - 383 GC01M203148
geneid 1 - 383 1116
genevestigator 1 - 383 P36222
germonline 1 - 383 ENSG00000133048
go 1 - 383 GO:0004568
go 1 - 383 GO:0005201
go 1 - 383 GO:0005529
go 1 - 383 GO:0005578
go 1 - 383 GO:0005615
go 1 - 383 GO:0006032
go 1 - 383 GO:0043169
h-invdb 1 - 383 HIX0001487
hgnc 1 - 383 HGNC:1932
hogenom 1 - 383 HBG443716
hovergen 1 - 383 HBG011684
inparanoid 1 - 383 P36222
interpro 1 - 383 IPR001223
interpro 1 - 383 IPR011583
interpro 1 - 383 IPR013781
interpro 1 - 383 IPR017853
ipi 1 - 383 IPI00002147
kegg 1 - 383 hsa:1116
medline 1 - 383 90328983
medline 1 - 383 94064658
medline 1 - 383 97386591
mim 1 - 383 601525
mim 1 - 383 611960
nextbio 1 - 383 4626
oma 1 - 383 FPLTNAI
orthodb 1 - 383 EOG90CM35
pdb 1 - 383 1HJV
pdb 1 - 383 1HJW
pdb 1 - 383 1HJX
pdb 1 - 383 1LA7
pdb 1 - 383 1NWR
pdb 1 - 383 1NWS
pdb 1 - 383 1NWT
pdb 1 - 383 1NWU
pdbsum 1 - 383 1HJV
pdbsum 1 - 383 1HJW
pdbsum 1 - 383 1HJX
pdbsum 1 - 383 1LA7
pdbsum 1 - 383 1NWR
pdbsum 1 - 383 1NWS
pdbsum 1 - 383 1NWT
pdbsum 1 - 383 1NWU
peptideatlas 1 - 383 P36222
pfam 1 - 383 PF00704
pharmgkb 1 - 383 PA26463
phosphosite 1 - 383 P36222
phylomedb 1 - 383 P36222
pir 1 - 383 A49562
pride 1 - 383 P36222
prosite 1 - 383 PS01095
proteinmodelportal 1 - 383 P36222
pubmed 1 - 383 12775711
pubmed 1 - 383 12851408
pubmed 1 - 383 14702039
pubmed 1 - 383 15489334
pubmed 1 - 383 18403759
pubmed 1 - 383 2375755
pubmed 1 - 383 8245017
pubmed 1 - 383 9244440
pubmed 1 - 383 9492324
refseq 1 - 383 NP_001267.2
smart 1 - 383 SM00636
string 1 - 383 P36222
supfam 1 - 383 SSF51445
ucsc 1 - 383 uc001gzi.2
unigene 1 - 383 Hs.382202
joined; genomic_dna 1 - 383 CAA69661.1
binding 141 - 141 Chitooligosaccharide
binding 263 - 263 Chitooligosaccharide
binding 352 - 352 Chitooligosaccharide
carbohyd 60 - 60 N-linked (GlcNAc...)
chain 22 - 383 Chitinase-3-like protein 1 /FTId=PRO_0000011965.
region 70 - 71 Chitooligosaccharide binding
region 97 - 100 Chitooligosaccharide binding
region 204 - 207 Chitooligosaccharide
variant 145 - 145 R -> G (in dbSNP:rs880633) /FTId=VAR_019838.
variant 311 - 311 I -> T (in dbSNP:rs1049407) /FTId=VAR_019839.
keyword 1 - 383 3D-structure
keyword 1 - 383 Complete proteome
keyword 1 - 383 Direct protein sequencing
keyword 1 - 383 Disulfide bond
keyword 1 - 383 Glycoprotein
keyword 1 - 383 Lectin
keyword 1 - 383 Polymorphism
keyword 1 - 383 Secreted
keyword 1 - 383 Signal
Molecular Weight 1 - 383 42625
1 hit 1 - 383 PF00704
false_neg 1 - 383 PS01095

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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