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C/EBP Alpha / CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.
| Gene Name: | CCAAT/enhancer binding protein (C/EBP), alpha |
| Synonyms: | CEBPA, C/EBP alpha, C/EBP-alpha, CEBP |
| Target Sequences: | NM_004364 NP_004355.2 P49715 |
Publications (1)
1
CCAAT/enhancer binding proteins alpha and beta regulate the tumor necrosis factor receptor 1 gene promoter. Bristol JA, Morrison TE, Kenney SC. Molecular immunology. 2009 46:2706-13. (WB, IP)
[PubMed:19523687]
[PMC:PMC2724677]
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C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (aa288-337) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (aa288-337) (HRP) Antibody
Chicken, Bovine, Rat, Rabbit, Mouse, Dog, Guinea pig, Pig, Chimpanzee, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (aa288-337) (FITC) Antibody
Chicken, Bovine, Rat, Rabbit, Mouse, Dog, Guinea pig, Pig, Chimpanzee, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
C/EBP Alpha / CEBPA Mouse anti-Human Monoclonal (5B7) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$459
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (aa304-330) Antibody
Mouse, Human
Flo, WB
Unconjugated
400 µl/$393
DNA Binding Phosphorylation
12 x 8-Well Microstrips
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Cell Lysates, Nuclear Lysates
1 Plate/$735
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (pSer21) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (1-80 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (aa265-314) Antibody
Human
WB
Unconjugated
100 µl/$424
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (pSer21) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Wheat Germ Extract
GST
65.8 kDa
2 µg/$439
C/EBP Alpha / CEBPA Mouse anti-Human Monoclonal (4E10) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (pSer21) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (aa304-330) Antibody
Mouse, Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (aa304-330) (FITC) Antibody
Mouse, Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (aa304-330) (APC) Antibody
Mouse, Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (aa304-330) (PE) Antibody
Mouse, Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (pSer21) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (p21) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (aa6-55) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (pSer21) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$328; 100 µl/$419
C/EBP Alpha / CEBPA Rabbit anti-Human Polyclonal (Met15) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
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