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The Immunohistochemistry Antibody Company
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LSBio Publications
The following are LSBio publications organized by topic. Here you can find white papers, press releases, and target overviews, and product references. LSBio white papers provide researchers with valuable scientific information resulting from research conducted in-house in the fields of immunohistochemistry and the generation and evaluation of antibodies for use in immunohistochemistry. Press releases are issued to announce significant product or business development events or milestones. In an effort to simplify navigation through those products associated with protein targets that have many family members, LSBio provides target overviews. Finally, LSBio is continually trying to collect publication references for papers in which LSBio products or services are used.
     CaspasesCaspases, or Cysteine Aspartate-specific Proteases, are enzymes involved in the signal transduction pathways of apoptosis and inflammation. Caspases are produced in cells as catalytically inactive zymogens which experience proteolytic processing at conserved aspartic residues. Upon cleavage, they produce a large and a small subunit that dimerize to form the active enzyme. The sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. There are two types of apoptotic caspases, initiator (apical) caspases and effector (executioner) caspases. [More]  CollagensCollagen is the most abundant protein in the animal kingdom. More than 20 different types of collagen are produced by numerous epithelial cells or fibroblasts in connective tissue in the body, although greater than 80 percent of the body’s collagen is type I, II or III. It is the major insoluble fibrous protein in connective tissue and in the extracellular matrix, serving to help tissues withstand stretching. Collagen is found in or constitutes many structures throughout the body, including tendon, skin, ligaments, teeth, bone, interstitial tissues, dentin, blood vessels, cartilage, the cornea, and muscle. [More]
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