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ZIC / ZIC1

Zic family member 1

Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'.

Gene Name: Zic family member 1
Synonyms: ZIC1, ZIC, Zic family member 1, Zinc finger protein ZIC 1, Zinc finger protein 201, ZNF201
Target Sequences: NM_003412 NP_003403.2 Q15915

Publications (1)

1
Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response. Lipchina I, Elkabetz Y, Hafner M, Sheridan R, Mihailovic A, Tuschl T, Sander C, Studer L, Betel D. Genes & development. 2011 25:2173-86. [PubMed:22012620] [PMC:PMC3205587]

☰ Filters
Antibodies (22)
Proteins (5)
ELISA Kits (1)
Cell-Based (1)
Over-Expression Lysate (2)
Primary (22)
Recombinant (3)
ZIC / ZIC1 (28)
Human (23)
Mouse (14)
Rat (5)
Bat (3)
Bovine (3)
Chicken (3)
Chimpanzee (3)
Gibbon (3)
Horse (3)
Monkey (3)
Pig (3)
IHC (9)
IHC-P (5)
WB (21)
ELISA (8)
ICC (5)
IF (2)
Peptide-ELISA (1)
rabbit (21)
mouse (1)
IgG (10)
monoclonal mc (1)
polyclonal pc (21)
3F7 (1)
96-Well Microplate (1)
APC Conjugated (1)
Biotin Conjugated (3)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (10)
aa6-34 (7)
aa50-99 (4)
aa25-42 (1)
No (28)
Adherent Cell Cultures (1)
GST, N-terminus (1)
GST, N-terminus + His, C-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (1)
ZIC / ZIC1 Antibody - ZIC1 antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ZIC / ZIC1 Rabbit anti-Human Polyclonal (aa50-99) Antibody
Human
WB
Unconjugated
100 µl/$424
ZIC / ZIC1 Antibody - ZIC1 antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ZIC / ZIC1 Rabbit anti-Human Polyclonal (aa50-99) (HRP) Antibody
Chicken, Bovine, Pig, Horse, Bat, Rat, Mouse, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
ZIC / ZIC1 Antibody - ZIC1 antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ZIC / ZIC1 Rabbit anti-Human Polyclonal (aa50-99) (Biotin) Antibody
Chicken, Bovine, Pig, Horse, Bat, Rat, Mouse, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
ZIC / ZIC1 Antibody - ZIC1 antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ZIC / ZIC1 Rabbit anti-Human Polyclonal (aa50-99) (FITC) Antibody
Chicken, Bovine, Pig, Horse, Bat, Rat, Mouse, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
ZIC / ZIC1 Antibody - 1:100 staining human brain tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ZIC / ZIC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ZIC / ZIC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
0.1 ml/$386
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ZIC / ZIC1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
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ZIC / ZIC1 Rabbit anti-Human Polyclonal (DY488) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
DY488 Conjugated
0.1 ml/$416
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ZIC / ZIC1 Rabbit anti-Human Polyclonal (DY550) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
DY550 Conjugated
0.1 ml/$416
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ZIC / ZIC1 Rabbit anti-Human Polyclonal (DY650) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
DY650 Conjugated
0.1 ml/$416
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ZIC / ZIC1 Rabbit anti-Human Polyclonal (aa25-42) Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
100 µl/$649
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ZIC / ZIC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
100 µl/$386
ZIC / ZIC1 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using ZIC1 Polyclonal Antibody at dilution of 1:65(×200)
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ZIC / ZIC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ZIC / ZIC1 Antibody - Detection limit for recombinant GST tagged ZIC1 is approximately 0.3 ng/ml as a capture antibody.
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ZIC / ZIC1 Mouse anti-Human Monoclonal (3F7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Select
ZIC / ZIC1 Rabbit anti-Human Polyclonal (aa6-34) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
ZIC / ZIC1 Rabbit anti-Human Polyclonal (aa6-34) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
200 µl/$952
Select
ZIC / ZIC1 Rabbit anti-Human Polyclonal (aa6-34) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
ZIC / ZIC1 Rabbit anti-Human Polyclonal (aa6-34) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
ZIC / ZIC1 Rabbit anti-Human Polyclonal (aa6-34) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
ZIC / ZIC1 Rabbit anti-Human Polyclonal (aa6-34) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
ZIC / ZIC1 Antibody - Western blot of ZIC1 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: RAW264.7 whole cell lysate.
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ZIC / ZIC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
ZIC / ZIC1 Antibody - ZIC1 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The ZIC1 antibody detected the ZIC1 protein (arrow).
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ZIC / ZIC1 Rabbit anti-Human Polyclonal (aa6-34) Antibody
Human
WB
Unconjugated
400 µl/$393
ZIC / ZIC1 Protein
Select
E. coli
GST, N-terminus + His, C-terminus
76.1 kDa
50 µg/$419
ZIC / ZIC1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
48.1 kDa
100 µg/$494
ZIC / ZIC1 Protein
Select
E. coli
His, N-Terminal
48.1 kDa
50 µg/$419
Viewing 1-25 of 28 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).