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Anti-WC1 / ATP7B Antibody (aa3-21, clone S62-29, SA) LS-C228608

Ordering

Wt. Vol. Conc. Price
100 µg - - $395

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Mouse Monoclonal [clone S62-29] (IgG1) to Human WC1 / ATP7B
Human, Mouse, Rat
IHC, Western blot, Immunoprecipitation
SA Conjugated

Details

Human WC1 / ATP7B
Mouse
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [S62-29]
Streptavidin (SA)
Protein G purified

Applications

IHC, Western blot, Immunoprecipitation

Specificity and Use

WC1 / ATP7B antibody was raised against synthetic peptide amino acids 3-21 (cytoplasmic N-terminus) of human Copper-transporting ATPase2.
aa3-21
Detects ~160kD in rat brain membrane preparations.
The applications listed above are for the unconjugated form of this antibody. The conjugated antibody has not been tested.

Packaging

PBS, pH 7.4, 0.09% sodium azide, 50% glycerol.
Store at -20°C.
For research use only.

About WC1 / ATP7B

P35670 NM_000053 NP_000044.2

ATP7B Antibody, Copper-transporting ATPase 2 Antibody, WC1 Antibody, Wilson disease Antibody, PWD Antibody, WD Antibody, Copper pump 2 Antibody, WND Antibody

ATP7b (ATPase, Cu++ Transporting, Beta Polypeptide), also known as Wilson Disease gene (WND) or mouse toxic milk gene, plays a key role in copper transport. Germ-line mutations in this gene cause so-called Wilson disease, which is characterized by the accumulation of toxic levels of copper in the liver, brain, and kidney resulting in extensive tissue damage and eventual death. ATP7b is expressed in a variety of carcinomas and appears to be associated with chemoresistance to cisplatin.

Requested From: United States
Date Requested: 10/23/2014

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