TNFSF10 / TRAIL

tumor necrosis factor (ligand) superfamily, member 10

TNFSF10 / TRAIL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Antibodies (124)

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TNFSF10 / TRAIL (185)

Reactivity

Human (118)

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TNFSF10 / TRAIL Antibody (1-80 aa, Internal) LS-C386509

Antibody:

TNFSF10 / TRAIL Rabbit anti-Human Polyclonal (1-80 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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TNFSF10 / TRAIL Antibody LS-C104433

Antibody:

TNFSF10 / TRAIL Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

500 µg/$326

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TNFSF10 / TRAIL Antibody LS-C18129

Antibody:

TNFSF10 / TRAIL Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

500 µg/$533

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TNFSF10 / TRAIL Antibody (HRP) LS-C549967

Antibody:

TNFSF10 / TRAIL Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

100 µl/$763

• Unconjugated
• HRP

• Unconjugated
• HRP

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TNFSF10 / TRAIL Antibody (aa114-281) LS-C292534

Antibody:

TNFSF10 / TRAIL Mouse anti-Human Monoclonal (aa114-281) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$292; 200 µl/$327; 500 µl/$443; 1 ml/$501; 2 ml/$626; 5 ml/$1,072

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TNFSF10 / TRAIL Antibody (aa95-281, clone 366G/76/3) LS-C191608

Antibody:

TNFSF10 / TRAIL Mouse anti-Human Monoclonal (aa95-281) (366G/76/3) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

100 µg/$860; 500 µg/$1,223

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Rat TNFSF10 / TRAIL Protein (Recombinant His-GST, N-terminus) (Pro115-Ala287) - LS-G11662

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

52.0 kDa

Price:

10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257

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Rat TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F23243

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$771

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Human TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F967

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

32 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$479

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Human TNFSF10 / TRAIL Protein (Recombinant Isoleucine Zipper Motif) (aa95-281) - LS-G3910

Source:

E. coli

Tag:

Isoleucine Zipper Motif

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 EU/µg protein (determined by LAL method).

Molecular Weight:

28kDa-82kDa

Price:

10 µg/$337

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TNFSF10 / TRAIL Antibody LS-C331936

Antibody:

TNFSF10 / TRAIL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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Mouse TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F23115

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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IHC-plus™ TNFSF10 / TRAIL Antibody (aa31-80) LS-B7802

(4.0) Rating

Antibody:

TNFSF10 / TRAIL Rabbit anti-Human Polyclonal (aa31-80) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

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TNFSF10 / TRAIL Antibody (C-terminal) LS-C254

Antibody:

TNFSF10 / TRAIL Rabbit anti-Human Polyclonal (C-terminal) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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TNFSF10 / TRAIL Antibody LS-C18676

Antibody:

TNFSF10 / TRAIL Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, IHC-Fr, IP, WB

Format:

Unconjugated

Price:

100 µg/$629

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Human TNFSF10 / TRAIL Protein (Recombinant His) (aa39-281) - LS-G21275

Source:

E. coli

Tag:

His

Molecular Weight:

32.5 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Mouse TNFSF10 / TRAIL (Sandwich ELISA) ELISA Kit - LS-F296

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

2 - 600 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$588

Select

IHC-plus™ TNFSF10 / TRAIL Antibody LS-B7420

(4.0) Rating

Antibody:

TNFSF10 / TRAIL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$485

Select

TNFSF10 / TRAIL Antibody (aa95-281, clone 2E5, Low Endotoxin) LS-C188227

Antibody:

TNFSF10 / TRAIL Mouse anti-Human Monoclonal (aa95-281) (Low Endotoxin) (2E5) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated, Low Endotoxin

Price:

0.5 mg/$869

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IHC-plus™ TNFSF10 / TRAIL Antibody (aa 39-281) LS-B14953

(4.0) Rating

Antibody:

TNFSF10 / TRAIL Rabbit anti-Human Polyclonal (aa 39-281) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

TNFSF10 / TRAIL Antibody LS-C771360

Antibody:

TNFSF10 / TRAIL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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TNFSF10 / TRAIL Antibody LS-C132601

Antibody:

TNFSF10 / TRAIL Rat anti-Mouse Monoclonal Antibody

Reactivity:

Mouse

Applications:

Flo

Format:

Unconjugated

Price:

100 µg/$587

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TNFSF10 / TRAIL Antibody (clone RIK-2) LS-C41050

Antibody:

TNFSF10 / TRAIL Mouse anti-Human Monoclonal (RIK-2) Antibody

Reactivity:

Human

Applications:

Flo

Format:

Unconjugated

Price:

100 µg/$292

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TNFSF10 / TRAIL Antibody (aa17-35, clone 55B709.3) LS-C493

Antibody:

TNFSF10 / TRAIL Mouse anti-Human Monoclonal (aa17-35) (55B709.3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

0.1 mg/$386

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Mouse TNFSF10 / TRAIL Protein (Recombinant His-S) (aa40-291) - LS-G11664

Source:

E. coli

Tag:

His-S

Molecular Weight:

35.9 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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