Human PPP1R13L / iASPP

Rabbit

Human (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Purified

Unmodified

Synthetic peptide corresponding amino acids 780-797 of human iASPP (isoform 1) protein.

aa780-797

Detects human inhibitor of apoptosis stimulating protein of p53 (iASPP), which plays a central role in regulation of apoptosis and transcription via its interaction with NFkB and p53 proteins. At present, the iASPP gene is thought to encode three isoforms; isoform 1 is predominantly located in the cytoplasm, whilst isoforms 2 and 3 are nuclear proteins. iASPP is highly expressed in the heart, placenta and prostate. iASPP has been shown to have oncogenic properties in human breast carcinomas.

• IHC - Paraffin
• Western blot (1:1000 - 1:5000)
• ELISA (1:40000 - 1:160000)

Western Blot: LS-C42655 detects a bands of approximately 100 and 50kD corresponding to iASPP isoforms 1 and 2 respectively.

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q8WUF5 NCBI: NM_006663 NP_006654.2