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PKP2 / Plakophilin 2

plakophilin 2

PKP2 / Plakophilin 2 is a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.

Gene Name: plakophilin 2
Synonyms: PKP2, ARVD9, Plakophilin 2, Plakophilin-2
Target Sequences: NM_004572 NP_004563.2 Q99959

Publications (1)

1
Progressive cardiac arrhythmias and ECG abnormalities in the Huntington's disease BACHD mouse model. Yujie Zhu, Isaac Shamblin, Efrain Rodriguez, Grace E Salzer, Lita Araysi, Katherine A Margolies, Ganesh V Halade, Silvio H Litovsky, Steven Pogwizd, Michelle Gray, Sabine Huke. Human molecular genetics. 2020 February;29:369-381. [Full Text Article] [PubMed:31816043] [PMC:PMC7015842] Related Antibodies: LS-B9231.

☰ Filters
Antibodies (37)
ELISA Kits (8)
Proteins (3)
Over-Expression Lysate (2)
Primary (37)
Recombinant (1)
Sandwich (8)
PKP2 / Plakophilin 2 (48)
Human (38)
Mouse (14)
Rat (11)
Bovine (5)
Chicken (1)
Dog (4)
Guinea pig (2)
Hamster (1)
Horse (4)
Monkey (2)
Pig (1)
Porcine (1)
Rabbit (3)
Sheep (3)
IHC (14)
IHC-P (6)
WB (31)
ELISA (9)
ICC (1)
IF (2)
IP (1)
Peptide-ELISA (3)
rabbit (32)
mouse (3)
goat (1)
guinea pig (1)
Product Group
IHCPlus (2)
IgG (19)
IgG1 (3)
monoclonal mc (3)
polyclonal pc (34)
8H6 (1)
Pkp2-518 (1)
PP2-62,86,150 (1)
96-Well Strip Plate (8)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (19)
aa571-849 (8)
aa838-866 (7)
aa143-192 (4)
C-Terminus (2)
610-690 aa, C-terminal (1)
Pro663 (1)
aa125-139 (1)
aa527-872 (1)
aa632-681 (1)
aa863-881 (1)
No (47)
Yes (1)
Plasma (2)
Serum (2)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
PKP2 / Plakophilin 2 Antibody - Anti-PKP2 / Plakophilin 2 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PKP2 / Plakophilin 2 Goat anti-Human Polyclonal (aa125-139) Antibody
Rabbit, Mouse, Dog, Rat, Hamster, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
PKP2 / Plakophilin 2 Antibody - Western blot of Plakophilin 2 antibody
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal (610-690 aa, C-terminal) Antibody
Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PKP2 / Plakophilin 2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
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PKP2 / Plakophilin 2 Mouse anti-Human Monoclonal (C-Terminus) (PP2-62,86,150) Antibody
Human
IHC
Unconjugated
5 ml/$768
PKP2 / Plakophilin 2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
92.6 kDa
20 µg/$150
PKP2 / Plakophilin 2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
92.6 kDa
100 µg/$494
PKP2 / Plakophilin 2 Antibody - PKP2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal (aa838-866) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PKP2 / Plakophilin 2 Protein - Recombinant Plakophilin 2 By SDS-PAGE
Select
E. coli
His-T7
34.7 kDa
50 µg/$470; 10 µg/$285; 200 µg/$937; 100 µg/$750; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252
PKP2 / Plakophilin 2 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal (aa838-866) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal (aa838-866) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal (aa838-866) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal (aa838-866) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal (aa838-866) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal (aa838-866) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
PKP2 / Plakophilin 2 Antibody - Western blot analysis of extracts from HeLa cells and HepG2 cells, using PKP2 antibody.
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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PKP2 / Plakophilin 2 Mouse anti-Human Monoclonal (aa527-872) (Pkp2-518) Antibody
Mouse, Sheep, Bovine, Rat, Human
IHC
Unconjugated
5 ml/$754
PKP2 / Plakophilin 2 Antibody - PKP2 / Plakophilin 2 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal (aa143-192) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
PKP2 / Plakophilin 2 Antibody - Western blot of Plakophilin 2 (P663) pAb in extracts from HeLa cells.
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal (Pro663) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
PKP2 / Plakophilin 2 Antibody - Western blot of recombinant PKP2 / Plakophilin 2.
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal (aa571-849) Antibody
Human
WB
Unconjugated
100 µl/$299; 200 µl/$336; 500 µl/$462; 1 ml/$525; 2 ml/$677; 5 ml/$1,136
PKP2 / Plakophilin 2 Antibody - WB of PKP2 / Plakophilin 2 antibody. All lanes: Anti-PKP2 at 0.5ug/ml. Lane 1: Rat Cardiac Muscle Tissue Lysate at 40ug. Lane 2: Human Placenta Tissue Lysate at 40ug. Lane 3: Rat Brain Tissue Lysate at 40ug. Lane 4: Rat Intestine Tissue Lysate at 40ug. Lane 5: HELA Whole Cell Lysate at 40ug. Lane 6: JURKAT Whole Cell Lysate at 40ug. Lane 7: 293T Whole Cell Lysate at 40ug. Lane 8: MCF-7 Whole Cell Lysate at 40ug. Lane 9: U87 Whole Cell Lysate at 40ug. Predicted bind size: 97KD. Observed bind size: 97KD.
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal (aa863-881) Antibody
Rabbit, Mouse, Guinea pig, Pig, Horse, Human, Monkey
WB
Unconjugated
10 µg/$318; 100 µg/$470
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PKP2 / Plakophilin 2 Guinea pig anti-Human Polyclonal Antibody
Mouse, Sheep, Bovine, Rat, Human
ICC, IHC, WB
Unconjugated
100 µl/$976
PKP2 / Plakophilin 2 Antibody - Immunohistochemistry image at a dilution of 1:200 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
PKP2 / Plakophilin 2 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PKP2 / Plakophilin 2 Antibody - Immunohistochemical analysis of Plakophilin 2 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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PKP2 / Plakophilin 2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$321
Viewing 1-25 of 48 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).