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Anti-NPC / NPC1 Antibody (Internal) LS-C113011

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $325

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Goat Polyclonal to Mouse NPC / NPC1
Mouse
ELISA
Unconjugated

Details

Mouse NPC / NPC1
Goat
Mouse (tested or 100% immunogen sequence identity)
Rat (at least 90% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

ELISA (1:16000)

Specificity and Use

NPC / NPC1 antibody was raised against synthetic peptide C-TYHTILKTSADYTD from an internal region of mouse NPC1 (NP_032746.2). Percent identity with other species by BLAST analysis: Mouse (100%), Rat (93%), Hamster (86%).
LS-E27388 - Lyophilized - 100 µg - $145.00
Internal
Mouse NPC1.
Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Preliminary experiments gave an approx 36kDa band in lysates of cell lines NIH3T3 and NSO after 1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 142kDa according to NP_032746.2. The 36kDa band was successfully blocked by incubation with the immunizing peptide.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About NPC / NPC1

NM_000271

NPC1 Antibody, NPC Antibody, Niemann-Pick C1 protein Antibody, Niemann-Pick disease, type C1 Antibody

NPC1 was identified as the gene that when mutated, results in Niemann-Pick C disease. NPC1 encodes a putative integral membrane protein containing motifs consistent with a role in intracellular transport of cholesterol to post-lysosomal destinations.

Requested From: United States
Date Requested: 8/28/2014

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