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Anti-NBN / NBS1 / Nibrin Antibody (phospho-Ser343) LS-C191097

Ordering

Wt. Vol. Conc. Price
50 µg - - $485

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Rabbit Polyclonal (IgG) to Human NBN / NBS1 / Nibrin
Human
Western blot
Unconjugated

Details

Human NBN / NBS1 / Nibrin
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Affinity purified

Applications

Western blot (1:500 - 1:1000)

Specificity and Use

NBN / NBS1 / Nibrin antibody was raised against synthetic phosphopeptide corresponding to human p95/NBS1 around the phosphorylation site of serine 343 (S-L-SP-Q-G).
pSer343
Human NBS1, phosphorylated at Ser343.

Packaging

PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at 12 months.
For research use only.

About NBN / NBS1 / Nibrin

O60934 NM_002485 NP_002476.2

NBN Antibody, ATV Antibody, AT-V2 Antibody, Nibrin Antibody, NBS1 Antibody, AT-V1 Antibody, NBS Antibody, p95 Antibody

Mutations in this Nibrin (NBN) are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Requested From: United States
Date Requested: 10/22/2014

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