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Anti-LTBR Antibody (Extracellular Domain, clone 5G11b, RPE) LS-C188250

Ordering

Wt. Vol. Conc. Price
- 100 tst - $435

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

LTBR Antibody LS-C188250 Images

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Flow Cytometry
Flow cytometry of mouse WEH1 cells with Rat anti-Mouse lymphotoxin receptor beta

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Rat Monoclonal [clone 5G11b] (IgG2a) to Mouse LTBR
Mouse
Flow Cytometry
RPE Conjugated

Details

Mouse LTBR
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [5G11b]
R. Phycoerythrin (RPE)
Protein G purified

Applications

Flow Cytometry (1:1)

Specificity and Use

LTBR antibody was raised against recombinant extracellular domain of LT beta R.
Extracellular Domain
Recognizes murine lymphotoxin-beta receptor (LT beta R), a member of the tumor necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. Clone 5G11b specifically recognizes surface expressed LT beta R. The clone is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release. This product is routinely tested on mouse WEHI cells.

Packaging

PBS, 0.09% sodium azide, 1% BSA, 5% sucrose
100 tst Distilled water
Store at +4°C. Do not freeze. Protect from light.
For research use only.

About LTBR

P36941 NM_002342 NP_002333.1

LTBR Antibody, D12S370 Antibody, CD18 Antibody, LT-BETA-R Antibody, Lymphotoxin B receptor Antibody, Lymphotoxin-beta receptor Antibody, TNFR3 Antibody, TNF-R-III Antibody, TNF-RIII Antibody, TNFCR Antibody, TNFRSF3 Antibody, TNFR-III Antibody, TNFR-RP Antibody, TNFR2-RP Antibody

Lymphotoxin Beta receptor functions as a receptor for the heterodimer of lymphotoxin-alpha and lymphotoxin-beta. It is expressed on the surface of most cell types including cells of epithelial and myeloid lineages. It plays a role in the development and organization of lymphoid tissues and stimulation of LTBR on dendritic cells has been shown to be critical for their homeostasis and expansion. Signaling via LTBR also been shown to induce the death of some adenocarcinoma cell lines.

Flow Cytometry

Flow Cytometry
Flow cytometry of mouse WEH1 cells with Rat anti-Mouse lymphotoxin receptor beta
 

Requested From: United States
Date Requested: 10/20/2014

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