Human LAMP1 / CD107a

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

B-T47

Unconjugated

Ion exchange chromatography

Preservative Free

Human U937 Caucasian hystiocytic lymphoma cell line

Recognizes human CD107a, otherwise known as LAMP-1 (lysosome-associated membrane protein-1), a 100-120kD type I integral lysosomal membrane glycoprotein and member of the LAMP family, which transfers between lysosomes, phagosomes and the plasma membrane, and may play a role in lysosomal membrane protection and in lectin-mediated cell adhesion. Studies have linked enhanced CD107a expression with the metastatic potential of some tumor cells, and with neurons and glial cells surrounding plaques in Alzheimer's patients. CD107a may also serve as a marker of mast cell activation.

• IHC - Paraffin
• Immunofluorescence
• Flow Cytometry

Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Method sheets are available on request. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

PBS

Store at 4°C. Do not freeze. Store undiluted. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P11279 NCBI: NM_005561 NP_005552.3