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KRT1 / CK1 / Cytokeratin 1
keratin 1
KRT1 / CK1 / Cytokeratin 1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
| Gene Name: | keratin 1 |
| Family/Subfamily: | Keratin , not assigned-Keratin |
| Synonyms: | KRT1, 67 kDa cytokeratin, CK-1, CK1, Cytokeratin 1, Cytokeratin-1, Epidermolytic hyperkeratosis 1, EHK, EHK1, Hair alpha protein, EPPK, NEPPK, K1, Keratin-1, KRTA, Type-II keratin Kb1, Type II keratin, Keratin 1, KRT1A |
| Target Sequences: | NM_006121 NP_006112.3 P04264 |
Publications (5)
1
Activated keratinocytes in the epidermis of hypertrophic scars. Machesney M, Tidman N, Waseem A, Kirby L, Leigh I. The American journal of pathology. 1998 152:1133-41.
[PubMed:9588880]
[PMC:PMC1858601]
2
Characterization and comparison of reconstructed skin models: morphological and immunohistochemical evaluation. Boelsma E, Gibbs S, Faller C, Ponec M. Acta dermato-venereologica. 80:82-8.
[PubMed:10877124]
3
A human keratin 10 knockout causes recessive epidermolytic hyperkeratosis. Mller FB, Huber M, Kinaciyan T, Hausser I, Schaffrath C, Krieg T, Hohl D, Korge BP, Arin MJ. Human molecular genetics. 2006 15:1133-41. (ICC)
[PubMed:16505000]
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(7)
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(5)
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KRT1 / CK1 / Cytokeratin 1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
KRT1 / CK1 / Cytokeratin 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
KRT1 / CK1 / Cytokeratin 1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
KRT1 / CK1 / Cytokeratin 1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
KRT1 / CK1 / Cytokeratin 1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
KRT1 / CK1 / Cytokeratin 1 Mouse anti-Human Monoclonal (34BetaB4) Antibody
Human
IHC, IHC-P, WB
Unconjugated
0.5 ml/$445
KRT1 / CK1 / Cytokeratin 1 Mouse anti-Human Monoclonal (3C10F7, 3C10G5) Antibody
ELISA, IHC, IHC-Fr, WB
Unconjugated
0.1 ml/$380
KRT1 / CK1 / Cytokeratin 1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
KRT1 / CK1 / Cytokeratin 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
KRT1 / CK1 / Cytokeratin 1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
E. coli
6His, N-terminus
69.9 kDa
1 mg/$1,679; 100 µg/$500; 20 µg/$364
KRT1 / CK1 / Cytokeratin 1 Rabbit Monoclonal Antibody
Human
IHC
Unconjugated
3 ml/$277; 100 µl/$301; 6 ml/$329; 200 µl/$367
KRT1 / CK1 / Cytokeratin 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
KRT1 / CK1 / Cytokeratin 1 Mouse anti-Human Monoclonal Antibody
Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$649
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$783
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
KRT1 / CK1 / Cytokeratin 1 Rabbit anti-Human Polyclonal (aa487-644) Antibody
Mouse, Rat, Pig, Human
ICC, IP, WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
KRT1 / CK1 / Cytokeratin 1 Mouse anti-Human Monoclonal (3C10F7, 3C10G5, PMC01, 4D12B3,3C10F7C11) Antibody
Human
IHC, WB
Unconjugated
100 µl/$518
KRT1 / CK1 / Cytokeratin 1 Mouse anti-Human Monoclonal (2A7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
KRT1 / CK1 / Cytokeratin 1 Guinea pig anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
100 µl/$914
KRT1 / CK1 / Cytokeratin 1 Rabbit anti-Mouse Polyclonal (aa189-497) Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
KRT1 / CK1 / Cytokeratin 1 Rabbit anti-Mouse Polyclonal (aa189-497) (Biotin) Antibody
Mouse, Rat
WB
Biotin Conjugated
100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248
KRT1 / CK1 / Cytokeratin 1 Mouse anti-Human Monoclonal (ABT-CK1) Antibody
Human
IHC
Unconjugated
0.05 ml/$268; 0.1 ml/$316
KRT1 / CK1 / Cytokeratin 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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