Human IL8 / Interleukin 8

Rabbit

Human (tested or 100% immunogen sequence identity)

IgG Polyclonal

Biotin

Purified

Unmodified

Recombinant human IL-8.

None

Recognizes human IL-8 (Interleukin-8), a 72 amino acid pro-inflammatory CXC chemokine designated CXCL8, secreted by endothelial cells and monocytes, which acts as a major chemoattractant for neutrophils and also T cells and basophils. IL-8, first isolated from osteosarcoma cells, contains the ELR-motif (N-Terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors. Cancer studies have demonstrated a role for IL-8 in the angiogenesis and growth of tumors. Previous nomenclature for IL-8 includes neutrophil activating protein 1(NAP-1), granulocyte chemotactic protein 1 (GCP-1), monocyte-derived neutrophil-activating peptide (MONAP) and protein 3-10C.

• Western blot (0.1 - 0.2 µg/ml)
• ELISA (0.15 - 0.3 µg/ml)

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

PBS

Sterile PBS containing 0.1% bovine Serum Albumin. For long term storage the addition of 0.09% sodium azide is recommended.

Before reconstitution store at 4°C. After reconstitution store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P10145 NCBI: NM_000584 NP_000575.1